Results 91 to 100 of about 558,548 (261)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The role of rootstock and its genetic background in plant mineral status: the relationship between petiole analyses and deficiency symptoms

OENO One
Rootstocks are an important means of adapting grapevine to environmental conditions whilst conserving the typical features of scion genotypes. Rootstocks not only provide tolerance to Phylloxera, but also ensure the supply of water and mineral nutrients
Marine Morel, Sarah Jane Cookson, Jean-Pierre Da Costa, Nathalie Ollat, Elisa Marguerit   +4 more
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Development of a lytic Ralstonia phage cocktail and evaluation of its control efficacy against tobacco bacterial wilt

Frontiers in Plant Science
IntroductionBacterial wilt (BW) caused by Ralstonia pseudosolanacearum is a devastating soil-borne disease. Bacteriophages are important biocontrol resources that rapidly and specifically lyse host bacteria, showing good application potential in ...
Haoxin He, Ke Yi, Lei Yang, Yongfeng Jing, Lifu Kang, Zhihao Gao, Dong Xiang, Ge Tan, Yunsheng Wang, Qian Liu, Lin Xie, Shiya Jiang, Tianbo Liu, Wu Chen   +13 more
doaj   +1 more source

New concepts of plant nutrition in production of the planting material: Hazelnut planting material production [PDF]

, 2006
U radu su predstavljeni rezultati ogleda u kome su ispitivani efekti primene novih vrsta đubriva i načina đubrenja u proizvodnji sadnog materijala leske. Ogled je postavljen na gajnjači đubrenoj pri meliorativnom đubrenju sa 100 t/ha stajnjaka. Kontrolna varijanta je bez primene mineralnih đubriva, dok je NPK (15:15:15) varijanta sa 600 kg/ha tretirana
Ličina, Vlado, Oparnica, Čedo
openaire  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Sustainable Cellulose Enables Blue Energy Toward Osmotic Energy Conversion

Nano-Micro Letters
Highlights This review highlights the design and application of cellulose-based membranes for salinity-gradient energy harvesting. Material composition, nanoscale structural engineering, surface functionalization, and ion-transport regulation strategies ...
Yingchao Wang, Jianping Shi, Qianhong Zhang, Hui Wu, Qingxian Miao, Liulian Huang, Lihui Chen, Yonghao Ni, Jianguo Li   +8 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source