Results 161 to 170 of about 553,806 (261)

Tyrosinase Inhibitors Among Flora of Lubelskie Region-Application of Bio-Chromatographic Approach and Zebrafish Model in Bioactivity Screening of Plant Material. [PDF]

Molecules
Kusio-Targońska K, Kosheva N, Wojtanowski KK, Gaweł-Bęben K, Beis D, Kukula-Koch W.   +5 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Genetic diversity and verification of plant material compliance of Cocoa (Theobroma cacao L.) in the Barombi-Kang Regional variety trial. [PDF]

PLoS One
Eyango NMC, Sounigo O, Fouet O, Tekeu H, Djocgoué FP, Efombagn MIB, Lanaud C.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Effect of nanoparticles on the ex-vitro performance of cryopreservation-derived plant material. [PDF]

PLoS One
Kulus D, Tymoszuk A, Kulpińska A, Viehmannova I, Wojnarowicz J, Szałaj U.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Comparison of Major Compounds in Essential Oils Steam Distilled from Fresh Plant Material of South African Hop Varieties. [PDF]

Life (Basel)
de Smidt O, du Plessis W, Zacharia PR, Manduna IT.   +3 more
europepmc   +1 more source

Grapevine Cane Extracts: Raw Plant Material, Extraction Methods, Quantification, and Applications. [PDF]

Biomolecules, 2020
Aliaño-González MJ, Richard T, Cantos-Villar E.   +2 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Erratum to: Assessment of Factors Influencing Urban Development; A Case Study of Niğde Ömer Halisdemir University Campus [PDF]

BIO Web of Conferences
Sandal Erzurumlu Gülden, Kahveci Barış   +1 more
doaj   +1 more source