Results 191 to 200 of about 675,070 (312)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

From Plant Material to Environmentally Friendly Plant Growth Stimulators: Betaine-Based Ionic Liquids. [PDF]

open access: yesACS Sustain Chem Eng
Olejniczak A   +6 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Karte des fünften Welttheils Polynesien oder Inselwelt, zum Gebrauch des Handbuchs der Erdbeschreibung und Geschichte dieses Welttheils [cartographic material] : 2 bande Leipzeig, 1793 /

open access: yes
Map of Western Pacific from China to the Marquesas, Pitcairn and Hawaiian islands. Shows Australia, Malay region, Polynesia and Melanesia. Relief shown by hachures.; "I.C. Peterman sculps Lips."; Published in: Handbuch einer vollstandigen Erdbeschreibung
Plant, Johann Traugott.
core  

Risks posed by the spread and dissemination of grapevine pathogens and their vectors

open access: yes, 2005
Several diseases of grapevine are transmissible by grafting as well as by aerial vectors. Risks of spread and dissemination of these diseases evolve from the potential introduction of the associated pathogens into new areas, and from the vectors ...
Maixner, Michael
core  

Three year retained orbital plant material. [PDF]

open access: yesAm J Ophthalmol Case Rep
Raikar DG, Winkler KP.
europepmc   +1 more source

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