Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Comparative Evaluation of the Volatile Profile of the Essential Oil, the Hydrolate and the Plant Material from <i>Origanum vulgare</i> subsp. <i>virens</i> Grown in Portugal. [PDF]
Freire CS +6 more
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Droplet Digital PCR for the Detection of <i>Pseudomonas savastanoi</i> pv. <i>savastanoi</i> in Asymptomatic Olive Plant Material. [PDF]
Tatulli G +4 more
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Tyrosinase Inhibitors Among Flora of Lubelskie Region-Application of Bio-Chromatographic Approach and Zebrafish Model in Bioactivity Screening of Plant Material. [PDF]
Kusio-Targońska K +5 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Genetic diversity and verification of plant material compliance of Cocoa (Theobroma cacao L.) in the Barombi-Kang Regional variety trial. [PDF]
Eyango NMC +6 more
europepmc +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Erratum to: Assessment of Factors Influencing Urban Development; A Case Study of Niğde Ömer Halisdemir University Campus [PDF]
Sandal Erzurumlu Gülden +1 more
doaj +1 more source

