Results 171 to 180 of about 552,867 (264)

Grapevine Cane Extracts: Raw Plant Material, Extraction Methods, Quantification, and Applications. [PDF]

Biomolecules, 2020
Aliaño-González MJ, Richard T, Cantos-Villar E.   +2 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Erratum to: Assessment of Factors Influencing Urban Development; A Case Study of Niğde Ömer Halisdemir University Campus [PDF]

BIO Web of Conferences
Sandal Erzurumlu Gülden, Kahveci Barış   +1 more
doaj   +1 more source

Effect of High-Tannin and -Polyphenol Plant Material Supplement on Rumen Fermentation, Nitrogen Partitioning and Nutrient Utilization in Beef Cattle. [PDF]

Animals (Basel)
Khejornsart P, Juntanam T, Gunun P, Gunun N, Cherdthong A.   +4 more
europepmc   +1 more source

Schisandra rubriflora Plant Material and In Vitro Microshoot Cultures as Rich Sources of Natural Phenolic Antioxidants. [PDF]

Antioxidants (Basel), 2020
Szopa A, Dziurka M, Granica S, Klimek-Szczykutowicz M, Kubica P, Warzecha A, Jafernik K, Ekiert H.   +7 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Elderberry Leaves with Antioxidant and Anti-Inflammatory Properties as a Valuable Plant Material for Wound Healing. [PDF]

Pharmaceuticals (Basel)
Studzińska-Sroka E, Paczkowska-Walendowska M, Woźna Z, Plech T, Szulc P, Cielecka-Piontek J.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Effect of the Type of Herbal Preparations (Powdered Plant Material vs. Dry Ethanolic Extracts) on the Bioaccessibility of Bearberry (Arctostaphylos uva-ursi (L.) Spreng.) Phytochemicals in Simulated Digestion Conditions. [PDF]

Molecules
Sęczyk Ł, Sugier D, Sugier P.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source