Results 81 to 90 of about 2,441,221 (311)

Acute and Sub-chronic Toxicity of Indole Alkaloids Extract from Leaves of Alstonia scholaris (L.) R. Br. in Beagle Dogs

open access: yesNatural Products and Bioprospecting, 2020
Alstonia scholaris (L.) R. Br., an evergreen tropical plant rich in indole alkaloids with significant physiological activity, is traditionally used to treat respiratory diseases in China.
Yun-Li Zhao   +9 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Visacane, an innovative quarantine tool for the exchange of pest and disease-free sugarcane germplasm [PDF]

open access: yes, 2011
Sugarcane varietal improvement can not exclusively rely upon exchange and introduction of genetic resources via true seeds (fuzz). It also requires the introduction of vegetative propagation material (cuttings, tissue-cultured plantlets).
Fernandez, Emmanuel   +4 more
core  

Kent Ekolojisi Açısından Diyarbakır Kenti Açık-Yeşil Alanlarında Kullanılan Bitki Materyallerinin Değerlendirilmesi

open access: yesResearch in Agricultural Sciences
Kentsel açık yeşil alanlar, kentlerdeki bahçeler, parklar, yeşil koridorlar, yol peyzajı ve benzeri alanları kapsamaktadır. Bu alanlar rekreasyonel aktiviteler dışında insan psikoloji ve insanlar arası sosyal etkileşimi sağlayan önemli mekânlardır ...
Medine Çelik, Hasan Yılmaz
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Development of a material processing plant for lunar soil [PDF]

open access: yes
Currently there is considerable interest in developing in-situ materials processing plants for both the Moon and Mars. Two of the most important aspects of developing such a materials processing plant is the overall system design and the integration of ...
Goettsch, Ulix, Ousterhout, Karl
core   +1 more source

Species-specific effects of elevated ozone on wetland plants and decomposition processes [PDF]

open access: yes, 2010
Seven species from two contrasting wetlands, an upland bog and a lowland rich fen in North Wales, UK, were exposed to elevated ozone (150 ppb for 5 days and 20 ppb for 2 days per week) or low ozone (20 ppb) for four weeks in solardomes.
Freeman, Chris   +2 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Participatory plant breeding in Denmark [PDF]

open access: yes, 2010
Plant breeding gets more and more concentrated on a couple of multinational companies, and financing plant breeding via the traditional royalty founded certification system exclusive for the specific needs in organic farming is not profitable in most ...
Andersen, Rikke, Borgen, Anders
core  

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