Results 171 to 180 of about 675,070 (312)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

An expert system for material handling equipment selection [PDF]

open access: yes
Manufacturing Systems are subject to increasingly frequent changes in demand in terms of number and type of products they produce. It is impractical to continually reconfigure the facilities, but it is possible to modify the material handling ...
Al-Meshaiei, Eisa Abdullah Eisa S.
core  

Acinetobacter baumannii's lifestyle includes soil-dwelling colonization of decaying plant material and airborne spread. [PDF]

open access: yesNat Commun
Wilharm G   +47 more
europepmc   +1 more source

THE OCCURRENCE OF ERGOTHIONEINE IN PLANT MATERIAL

open access: yesJournal of Biological Chemistry, 1956
D B, MELVILLE, S, EICH
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

ANTITHIAMINE ACTIVITY OF PLANT MATERIALS

open access: yesJournal of Biological Chemistry, 1946
P H, WESWIG, A M, FREED, J R, HAAG
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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