Results 71 to 80 of about 8,310,098 (237)
Western New Britain [cartographic material] : provisional map /
1st rev. [ed.]. Topographic map of Western New Britain. Relief shown by contours and spot heights.; "This map supercedes previous edition printed in August 1943."; Includes index to adjoining sheets and reliability diagram.; Also available in an ...
United States. Army. South West Pacific Area. Base Map Plant.
core
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Central New Britain [cartographic material] : provisional map /
1st rev. [ed.]. Topographic map of Central New Britain. Relief shown by contours and spot heights.; "This map supercedes previous edition printed in August, 1943."; Includes index to adjoining sheets and reliability diagram.; National Library of ...
United States. Army. South West Pacific Area. Base Map Plant.
core
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Alstonia scholaris (L.) R. Br. (Apocynaceae) is an evergreen tree that has been used to treat lung diseases. In this study, the toxicity profile of indole alkaloids from leaves of A. scholaris was investigated.
Yun-Li Zhao +10 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Vitu Islands, New Britain [cartographic material] : strategic map /
2nd ed. Topographic map of Vitu Islands, New Britain. Relief shown by spot heights.; The first edition was printed by Aust. L.H.Q., 1942.; Includes index to adjoining sheets and reliability diagram.; Also available in an electronic version via the ...
United States. Army. South West Pacific Area. Base Map Plant.
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source

