Results 111 to 120 of about 7,278,259 (348)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A rule-based functional-structural model of rice considering source and sink functions [PDF]

As a first step towards a generic genotype-phenotype model of rice, we present here a model of the growth and morphology of rice in combination with ecophysiological processes using the technique of functional-structural plant modelling (FSPM) and the ...
Buck-Sorlin, G.H., Henke, M., Kurth, W., Xu, L., Zhu, Jun   +4 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

The Impact of the Long-Distance Transport of a BEL1-Like Messenger RNA on Development [PDF]

, 2012
BEL1- and KNOTTED1-type proteins are transcription factors from the three-amino-loop-extension superclass that interact in a tandem complex to regulate the expression of target genes.
Gonzalez, Daniel Hector, Hannapel, David J., Lin, Tian, Sharma, Pooja, Viola, Ivana Lorena   +4 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Morfologia do fruto, da semente e morfo-anatomia da plântula de Vitex megapotamica (Spreng.) Moldenke (Lamiaceae) Fruit and seed morphology and morpho-anatomy of seedlings of Vitex megapotamica (Spreng.) Moldenke (Lamiaceae)

Acta Botânica Brasílica, 2009
Vitex megapotamica (tarumã) é espécie arbórea, decídua, com ocorrência, no Brasil, desde Minas Gerais até o Rio Grande do Sul. Visando à caracterização morfológica do fruto, da semente e morfo-anatômica da plântula, frutos desta espécie foram coletados e
Nelson Luiz Cosmo, Alessandra Mara Gogosz, Antônio Carlos Nogueira, Cleusa Bona, Yoshiko Saito Kuniyoshi   +4 more
doaj   +1 more source

Nitrogen forms affect root structure and water uptake in the hybrid poplar [PDF]

, 2011
The study analyses the effects of two different forms of nitrogen fertilisation (nitrate and ammonium) on root structure and water uptake of two hybrid poplar (Populus maximowiczii x P. balsamifera) clones in a field experiment.
A Clemensson-Lindell, A Hodge, A Karacic, AH Fitter, AH Fitter, B Huang, C Glynn, CC Kern, Christian Messier, D Guo, DA Rose, DI Dickmann, DM Eissenstat, DM Eissenstat, E Salas, F Ripullone, Frank Berninger, GA Bauer, GB West, H Coners, H Ozier-Lafontaine, H Poorter, HP Harvey, HP Harvey, J Lopez-Bucio, J Lynch, JA Parkinson, JEK Cooke, JS King, JS King, KS Pregitzer, KS Pregitzer, KS Pregitzer, L Coll, Lluís Coll, M Noordwijk van, MD Coleman, P Armengaud, R Driesche Van den, R Fujimaki, RMA Block, S Delagrange, Susy Domenicano, T Ericsson, T Sakuratani, TJ Albaugh, WTM Woolfolk, X Min   +47 more
core   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Are sun- and shade-type anatomy required for the acclimation of Neoregelia cruenta?

Anais da Academia Brasileira de Ciências, 2013
Sun and shade plants are often discriminated by a number of sun- and shade-type anatomies. Nonetheless, we propose that among tank-bromeliads, changes in rosette architecture satisfy the requirements for coping with contrasting light levels.
FERNANDA REINERT, MARCOS V. LEAL-COSTA, NÍCIA E. JUNQUEIRA, ELIANA S. TAVARES   +3 more
doaj  

Growth Strategy of Rhizomatous and Non-Rhizomatous Tall Fescue Populations in Response to Defoliation

Agriculture, 2015
The aim of this study was to determine the morphology of rhizome production, in two contrasting rhizomatous (R) and non-rhizomatous (NR) tall fescue (Schedonorus arundinaceus (Schreb.) Dumort) populations, and to assess whether rhizome production is ...
Racheal H. Bryant, Cory Matthew, John Hodgson   +2 more
doaj   +1 more source