Results 81 to 90 of about 2,516,713 (283)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
EMPHASIS – European Multi-environment Plant pHenotyping And Simulation InfraStructure
, 2015 The EMPHASIS proposal aim to establish a European Infrastructure within the ESFRI framework, based on national phenotyping infrastructure (Belgium, France, Germany and UK).
Tardieu, Francois +7 more
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
M3P: The "Montpellier Plant Phenotyping Platforms"
, 2015 The research group LEPSE, ranked among the top 5% research group in ecophysiology worldwide in 2014 by a panel of experts is developing high throughput phenotyping platforms for more than 15 years.
Welcker, Claude +10 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
An Overview of Machine Learning Applications on Plant Phenotyping, with a Focus on Sunflower
AgronomyMachine learning is a widespread technology that plays a crucial role in digitalisation and aims to explore rules and patterns in large datasets to autonomously solve non-linear problems, taking advantage of multiple source data.
Luana Centorame +4 more
doaj +1 more source
Opportunities and Limitations of Crop Phenotyping in Southern European Countries
Frontiers in Plant Science, 2019 The Mediterranean climate is characterized by hot dry summers and frequent droughts. Mediterranean crops are frequently subjected to high evapotranspiration demands, soil water deficits, high temperatures, and photo-oxidative stress.
Joaquim Miguel Costa +11 more
doaj +1 more source
Phenotyping and beyond: modelling the relationships between traits
, 2014 International audiencePlant phenotyping technology has become more advanced with the capacity to measure many morphological and physiological traits on a given individual.
Vile, Denis, Granier, Christine, C.
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source