Results 121 to 130 of about 29,856 (265)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Kinome profiling reveals an interaction between jasmonate, salicylate and lifht control of hyponastic petiole growth in Arabidopsis thaliana

, 2010
Plants defend themselves against infection by biotic attackers by producing distinct phytohormones. Especially jasmonic acid (JA) and salicylic acid (SA) are well known defense-inducing hormones.
Voesenek, L.A.C.J., Pieterse, C.M.J., van Zanten, M., Millenaar, F.F., Peeters, A.J.M., Leon Reyes, H.A., Ritsema, T.   +6 more
core  

The importance of assessing clinical phenomena in Mechanical Turk research

, 2016
Amazon.com's Mechanical Turk (MTurk) website provides a data collection platform with quick and inexpensive access to diverse samples. Numerous reports have lauded MTurk as capturing high-quality data with an epidemiological sample that is more ...
Çek, Demet, Timpano, Kiara R, Arditte, Kimberly A, Shaw, Ashley M   +3 more
core   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Zinc Homeostasis and isotopic fractionation in plants: a review

, 2016
Aims Recent advances in mass spectrometry have demonstrated that higher plants discriminate stable Zn isotopes during uptake and translocation depending on environmental conditions and physiological status of the plant.
Weiss, DJ, Caldelas, C
core   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Beneficial effects of bacteria-plant communication based on quorum sensing molecules of the N-acyl homoserine lactone group.

, 2016
Bacterial quorum sensing (QS) mechanisms play a crucial role in the proper performance and ecological fitness of bacterial populations. Many key physiological processes are regulated in a QS-dependent manner by auto-inducers, like the N-acyl homoserine ...
Schenk, Sebastian T., Schikora, A., Schikora, Adam, Schenk, S.T., Hartmann, A., Hartmann, Anton, schenk, sebastian   +6 more
core   +1 more source

Simultaneous Electrochemical Detection of NGF and proNGF Under Native Conditions Using Molecularly Imprinted Polymers: Toward Point‐of‐Care Diagnosis of Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
This study relies on the development of a new sensor that can detect two closely related proteins involved in Alzheimer's disease at the same time. Unlike traditional methods, it works in natural conditions and does not require sample pretreatment. The device is highly sensitive and was successfully tested on patient samples, offering promises for ...
Giulia Siciliano, Alfredo De Cillis, Elena Clabassi, Francesco Ferrara, Maria Serena Chiriacò, Antonio Turco, Clarissa Loiola, Chiara Zecca, Maria Teresa Dell'Abate, Giancarlo Logroscino, Giuseppe Gigli, Francesca Malerba, Elisabetta Primiceri   +12 more
wiley   +1 more source

A Two-Stage Screening-to-Optimization Approach with Mechanistic Model Analysis: Enhancing Anthocyanin in Lettuce Without Yield Loss

Plants
Enhancing anthocyanin accumulation in red-leaf lettuce grown in plant factories often incurs yield penalties. Here we propose a two-stage screening-to-optimization framework integrated with mechanistic modeling to resolve this tradeoff.
Zhihao Wei, Wei Fang, Chen-Kang Huang
doaj   +1 more source