Results 121 to 130 of about 6,061,198 (342)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Application of Artificial Intelligence and Predictive Analysis in Plant Physiology Teaching and Research

Scientific Papers Animal Science and Biotechnologies
Artificial Intelligence (AI) and predictive analysis are transforming plant physiology education and research. These technologies allow for the efficient analysis of large datasets, improving our understanding of complex plant processes and their ...
Eugen Cătălin Zoican, Ioan Bogdan Peț, Alexandra Ferencz, Magda Miruna Morariu, Andreea Cîrstea, Raul Pașcalău, G. V. Milaciu   +6 more
doaj  

From models to crop species: caveats and solutions for translational metabolomics

Frontiers in Plant Science, 2011
Although plant metabolomics is largely carried out on Arabidopsis it is essentially genome-independent, and thus potentially applicable to a wide range of species.
Takayuki eTohge, Tabea eMettler, Stephanie eArrivault, Adam James Carroll, Mark eStitt, Alisdair eFernie   +5 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Do the design concepts used for the space flight hardware directly affect cell structure and/or cell function ground based simulations [PDF]

The use of clinostats and centrifuges to explore the hypogravity range between zero and 1 g is described. Different types of clinostat configurations and clinostat-centrifuge combinations are compared.
Chapman, David K.
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Aubergine (Solanum melogena L.) [PDF]

, 2009
This tool focuses on the aubergine crop. It provides information on the plant physiology, the traditional varieties available in Italy as well as the seed production, conservation and ...
Bocci, Riccardo, Nonne, Maria Francesca
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

アオミドロにおける仮根分化Ⅰ仮根形成の基本的諸特徴Ⅱ仮根誘導の赤色光と近赤外光による光可逆性 [PDF]

This is an author's original PDF of an article accepted for publication in Plant and Cell Physiology. The version of record Nagata, Y. (1973, 9) Rhizoid differentiation in Spirogyra. Basic features of rhizoid formation. Plant and Cell Physiol. 14(3), 531-
ナガタ, ヨウコ, 長田, 洋子
core  

An international collaborative research network helps to design climate robust rice systems [PDF]

, 2009
Rice is the world's most important staple food. Although mainly produced in Asia (91%), it is consumed on all continents and its global importance and consumption is increasing.
Bastiaens, L., Bouman, Bas, Dingkuhn, Michaël, Gaydon, Donald, Hasegawa, Toshihiro, Heinemann, Alexandre, Kiepe, Paul, Lafarge, Tanguy, Luquet, Delphine, Masood, A., Meinke, H., Rodenburg, Jonne, Van Oort, P.A.J., Yan, J., Yin, Xinyou   +14 more
core