Predicting the contribution of single trait evolution to rescuing a plant population from demographic impacts of climate change. [PDF]
Evol LettCampbell DR, Powers JM, Kipness J.
europepmc +1 more source
Altitude, habitat type and herbivore damage interact in their effects on plant population dynamics. [PDF]
PLoS One, 2018 Dostálek T, Rokaya MB, Münzbergová Z.
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A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
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Changes in reproduction mediate the effects of climate change and grassland management on plant population dynamics. [PDF]
Ecol ApplAndrzejak M +3 more
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Period-3 dominant phase synchronisation of Zelkova serrata: border-collision bifurcation observed in a plant population. [PDF]
Sci Rep, 2019 Sakai K +4 more
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
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Tourist Trampling on a Peripheral Plant Population Restricted to an Urban Natural Area in the Capo Sant'Elia Promontory (Sardinia, W-Mediterranean Basin). [PDF]
Plants (Basel)Cogoni D, Calderisi G, Collu D, Fenu G.
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Source-to-Sink Translocation of Carbon and Nitrogen Is Regulated by Fertilization and Plant Population in Maize-Pea Intercropping. [PDF]
Front Plant Sci, 2019 Zhao Y +6 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
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