Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Machine learning-based prediction of dynamic heterosis for plant height with pathway biomarkers in rice. [PDF]
Dan Z, Chen Y, Huang W.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Variable suppression by mycorrhiza of root-lesion nematode Pratylenchus thornei reproduction among mung bean genotypes has implications for phenotyping. [PDF]
Adhikari B +4 more
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
QTL-Seq and pyramiding of yield-related loci from wild rice (<i>Oryza rufipogon</i> Griff.) introgression lines under nutrient-deficient conditions. [PDF]
Adu BG +6 more
europepmc +1 more source
High-resolution quantitative trait loci mapping and pyramiding effects of candidate genes for plant height in soybean. [PDF]
Sha D +16 more
europepmc +1 more source
Correction: Mapping of quantitative trait locus for resistance to anthracnose in a population derived from genotypes PI 527538 and Ervilha of common bean. [PDF]
Mulube M +11 more
europepmc +1 more source
Spectrophotometric Estimation of Polyphenolic Compounds in Willowherbs (<i>Epilobium angustifolium</i> L. and <i>E. hirsutum</i> L.) and Implications for Genetic Resource Conservation. [PDF]
Labokas J, Vilutytė A.
europepmc +1 more source
CartograPlant: bridging genomic, phenotypic, and environmental data to advance plant resilience and eco-evolutionary insight. [PDF]
Lind BM +7 more
europepmc +1 more source

