Results 91 to 100 of about 162,454 (265)

Kinetic study, byproducts characterization and photodegradation pathway of profoxydim in a biochar water soil system

Scientific Reports
The study focused on the photodegradation of profoxydim, a low-toxicity cyclohexanedione herbicide commonly used in rice crops, under simulated sunlight conditions. Profoxydim’s behavior in paddy field conditions is not well understood, and this research
Álvaro Cervantes-Díaz, Juan Carlos Nieto-Carmona, Beatriz Sevilla-Morán, José Luis Alonso-Prados, Pilar Sandín-España   +4 more
doaj   +1 more source

Unveiling Coformulants in Plant Protection Products by LC-HRMS Using a Polyhydroxy Methacrylate Stationary Phase. [PDF]

J Agric Food Chem, 2023
Martín-García B, Romero-González R, Vidal JLM, Garrido Frenich A.   +3 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Methods and Strategies for Biomonitoring in Occupational Exposure to Plant Protection Products Containing Glyphosate. [PDF]

Int J Environ Res Public Health, 2023
Moldovan H, Imre S, Duca RC, Farczádi L.   +3 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Mixture effects of co-formulants and two plant protection products in a liver cell line. [PDF]

EXCLI J, 2023
Feiertag K, Karaca M, Fischer B, Heise T, Bloch D, Opialla T, Tralau T, Kneuer C, Marx-Stoelting P.   +8 more
europepmc   +1 more source

Use of a pearl mill for the production of plant protection products

Technical Sciences, 2019
Production of plant protection products is one of the most innovative branches of the chemical industry for agriculture requiring considerable financial outlays, which is associated with the needs of farmers. This is because the intention of farmers is to obtain higher yields and search for substances with properties independent of weather conditions ...
Sławomir Tomaszewski, Żaneta Grzywacz, Katarzyna Szwedziak   +2 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Risk Assessment and Fitness Cost of Tetraniliprole Resistance in Ostrinia furnacalis (Lepidoptera: Crambidae)

Agronomy
Asian corn borer (ACB), Ostrinia furnacalis, is a predominant pest species that is widely distributed across major corn-growing regions in China. Tetraniliprole, a novel diamid insecticide, exhibited good efficacy on lepidopteran insect pests and was ...
Tingting Xu, Fei Hu, Ran Yue, Benjin Hu, Sijia Bi, Youmin Tong, Lina Xu   +6 more
doaj   +1 more source