Results 51 to 60 of about 2,532,605 (279)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Development of Polymer Resins using Neural Networks

Polímeros, 2002
The development of polymer resins can benefit from the application of neural networks, using its great ability to correlate inputs and outputs. In this work we have developed a procedure that uses neural networks to correlate the end-user properties of a
Fabiano A. N. Fernandes, Liliane M. F. Lona   +1 more
doaj   +1 more source

Elution strategies for recovery of nickel and cobalt from laterite tails through scavenging resin-in-pulp [PDF]

, 2012
Ion exchange resin has been used to recover value metal in the uranium and gold industry through resin-in-pulp/leach and similar carbon-in-leach/pulp processes for decades.
Vaughan, James, Littlejohn, P., Vaughan, J., Nikoloski, A., Littlejohn, Patrick, Nikoloski, Aleks   +5 more
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Abundant surface resins present on Middle Devonian land plants

Communications Earth & Environment
Plant resins, serving various essential ecological functions, have traditionally been associated with conifers and angiosperms. Previously, the oldest known resin was identified in the late Carboniferous.
Daofu Song, Tieguan Wang, Ningning Zhong, Honghe Xu, Hao Wang, Zhengang Lu, Yue Liu, Yun Wang   +7 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Bioactive Potential of 3D-Printed Oleo-Gum-Resin Disks: B. papyrifera, C. myrrha, and S. benzoin Loading Nanooxides—TiO2, P25, Cu2O, and MoO3

Bioinorganic Chemistry and Applications, 2017
This experimental study investigates the bioactive potential of filaments produced via hot melt extrusion (HME) and intended for fused deposition modeling (FDM) 3D printing purposes.
Diogo José Horst, Sergio Mazurek Tebcherani, Evaldo Toniolo Kubaski, Rogério de Almeida Vieira   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Analytical methods applied to diverse types of Brazilian propolis

Chemistry Central Journal, 2011
Propolis is a bee product, composed mainly of plant resins and beeswax, therefore its chemical composition varies due to the geographic and plant origins of these resins, as well as the species of bee.
Marcucci Maria, Barbosa da Silva Cunha Ildenize, Sawaya Alexandra   +2 more
doaj   +1 more source