Results 101 to 110 of about 597,854 (214)

More eyes on the prize: open-source data, software and hardware for advancing plant science through collaboration. [PDF]

AoB Plants, 2023
Coleman GRY, Salter WT.
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Translocation of Foliar-Applied Nanoparticles: A Critical Review From a Plant Science Perspective. [PDF]

Physiol Plant
Pinna A, Husted S.
europepmc   +1 more source

Editorial: Phytochemicals in ornamental plants: Synthesis, nutraceutical prospects and applied focus-Women in plant science series. [PDF]

Front Plant Sci, 2022
Schmitzer V, Choo WS, Urbanek Krajnc A.
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Importance of measuring and reporting environmental conditions across plant science subdisciplines. [PDF]

Plant Physiol
Vincent C, Leisner CP, Locke AM, Pelech E, Schmiege SC, Sharkey TD, Tejera-Nieves M, Alade DO, Cardoso AA, Cho A, De Silva K, Dziedzic N, Gill AR, Kaur R, Lane SL, Michalczyk GZ, Singh A, Teshome DT.   +17 more
europepmc   +1 more source

Editorial: Protein posttranslational modifications in plant responses to abiotic stress - Women in plant science series. [PDF]

Front Plant Sci, 2022
Sirko A, Gotor C, Wawrzyńska A.
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Focus issue editorial: Numeracy, realism, and relevance in plant science. [PDF]

Plant Physiol
Brophy JAN, Lin YR, Shanks JV, Smith AG, Williams M, Hanson AD.   +5 more
europepmc   +1 more source

Removing systemic barriers to equity, diversity, and inclusion: Report of the 2019 Plant Science Research Network workshop "Inclusivity in the Plant Sciences". [PDF]

Plant Direct, 2022
Henkhaus NA, Busch W, Chen A, Colón-Carmona A, Cothran M, Diaz N, Dundore-Arias JP, Gonzales M, Hadziabdic D, Hayes RA, MacIntosh GC, Na A, Nyamasoka-Magonziwa B, Pater D, Peritore-Galve FC, Phelps-Durr T, Rouhier K, Sickler DB, Starnes JH, Tyler QR, Valdez-Ward E, Vega-Sánchez ME, Walcott RR, Ward JK, Wyatt SE, Zapata F, Zemenick AT, Stern DB.   +27 more
europepmc   +1 more source