Results 311 to 320 of about 2,784,419 (339)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

RETRACTION: lncRNA‐PDPK2P Promotes Hepatocellular Carcinoma Progression Through the PDK1/AKT/Caspase 3 Pathway

Molecular Oncology, EarlyView.
RETRACTION: W. Pan, W. Li, J. Zhao, Z. Huang, J. Zhao, S. Chen, C. Wang, Y. Xue, F. Huang, Q. Fang, J. Wang, D. Brand, and S. G. Zheng, “lncRNA‐PDPK2P Promotes Hepatocellular Carcinoma Progression Through the PDK1/AKT/Caspase 3 Pathway,” Molecular Oncology 13, no. 10 (2019): 2246–2258, https://doi.org/10.1002/1878-0261.12553.
wiley   +1 more source

Multivariate approaches in plant science [PDF]

Phytochemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Jakob Schultz, David M. Gottlieb, Ib Søndergaard, Susanne W. Bruun, Susanne Jacobsen   +4 more
openaire   +3 more sources

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Carbohydrate Microarrays in Plant Science

2012
Almost all plant cells are surrounded by glycan-rich cell walls, which form much of the plant body and collectively are the largest source of biomass on earth. Plants use polysaccharides for support, defense, signaling, cell adhesion, and as energy storage, and many plant glycans are also important industrially and nutritionally.
Fangel, Jonatan Ulrik, Pedersen, Henriette Lodberg, Vidal Melgosa, Silvia, Ahl, Louise Isager, Asunción Salmeán, Armando, Madsen, Jack Egelund, Rydahl, Maja Gro, Clausen, Mads Hartvig, Willats, William George Tycho   +8 more
openaire   +4 more sources

Antibodies in plant science

Acta Botanica Neerlandica, 1991
In this review, we seek to identify those areas where the use of immunological techniques can be an invaluable aid to plant scientists and to outline techniques and approaches available for dealing with a variety of problems. We do not seek to provide an exhaustive coverage of the literature but instead have included those general texts, reviews and ...
Chris Hawes, R. A. Priestley, David E. Evans, M. Dewey, D. Horsley, R. Hull, Julian O. D. Coleman   +6 more
openaire   +2 more sources

A New Focus on Plant Sciences

Science, 2010
Plants are essential to the survival of our planet—to its ecology, biodiversity, and climate. They maintain human health by providing the basis for nutrition, shelter, clothing, and energy. The study of plants has yielded fundamental insights that have reshaped our understanding of the world and has enabled major human needs to be addressed.
Steven J. McCormick, Robert Tjian
openaire   +3 more sources

Forensic plant science

Australian Journal of Forensic Sciences, 2016
For an application of science that attempts to answer forensic questions, forensic botany would not be high on the radar screen, and yet this is the third quite recent book on forensic botany.
openaire   +2 more sources

Plant science in the age of phage

Trends in Plant Science, 2004
A wide range of foreign proteins can be expressed at the surface of bacteriophage particles by fusion to phage coat proteins. This powerful molecular technique, known as phage display, has been embraced by the animal and medical research communities but has received less attention from plant scientists.
Bernal Giraldo, Adriana Jimena, Willats, William George Tycho   +1 more
openaire   +3 more sources