Results 141 to 150 of about 2,793,637 (301)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Corrigendum to "Effect of Plant Spacing on Yield and Yield Components of Tomato (Solanum lycopersicum L.) in Shewarobit, Central Ethiopia". [PDF]

Scientifica (Cairo), 2020
Amare G, Gebremedhin H.
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Pengaruh Kerapatan Tanaman terhadap Pertumbuhan dan Hasil Benih Kentang (Solanum Tuberosum L.) Generasi Satu (G1) Varietas Granola

Planta Tropika: Jurnal Agrosains, 2017
The experiment was conducted in Experimental Research Station of Indonesian Institute for Vegetable Research (IIVR) at Cikole, Lembang city, West Bandung in September to December 2015. The research area was located in 1250 m above sea level with the type
Deden Fatchullah
doaj  

Morphological characteristics, dry matter yield, and nutritive value of maralfalfa grass (Pennisetum spp.) grown under different planting densities in the central highlands of Ethiopia

Frontiers in Animal Science
IntroductionMaralfalfa grass (Pennisetum spp.) is known for its high dry matter productivity and nutritive value. However, information on agronomic management practices to improve yield and nutritive value in Ethiopia is sparse.Materials and methodThe ...
Gezahegn Mengistu, Gezahagn Kebede, Mulisa Faji, Fekede Feyissa, Kedir Mohammed, Aemiro Kehaliew, Diriba Geleti, Muluneh Minta, Mulubrhan Balehegn, Mulubrhan Balehegn, Estebah F. Rios, Adegbola T. Adesogan, Adegbola T. Adesogan, Jose C. B. Dubeux, Kenneth J. Boote   +14 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Response of Bt cotton hybrids to different plant spacing under rainfed condition [PDF]

, 2010
The field experiment was conducted at Department of Agronomy, Marathwada Agricultural University, Parbhani during the Kharif season, 2008-09 to find out the response of Bt cotton hybrids to different plant spacings.
Solunke, S S, Pendharkar, A, Kote, G M, Sawargaonkar, G L   +3 more
core  

Plant PhysioSpace: navigating the “space” of plant stress responses [PDF]

Plant Physiology, 2021
openaire   +2 more sources