Results 71 to 80 of about 2,793,637 (301)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2021 Field trail was conducted at the Research Farm of Cotton Section, Department of Genetics & Plant Breeding, CCS HAU, Hisar (Lat 29ᵒ 10\u27 N, Long 75ᵒ 46\u27 E and 215.2 m msl) during Kharif season of 2015.
Singh, Amit +13 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Text spacing considerations for children’s on-screen reading [PDF]
, 2008 This investigation seeks to uncover the insights of three integral and inter-related participants in the creation and use of on-screen reading material for children’s learning.
Vanderschantz, Nicholas +1 more
core
Polytechnic Journal, 2019 A field study was conducted at Grdarasha Research Station of the College of Agriculture/Salahaddin University, Erbil, during growing winter season of 2017, to study the effect of plant spacing on some yield and quality of chickpea varieties.
Sumaya Ahmed Abdullah +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Plant Spacing: A Key Husbandry Practice for Rainy Season Cabbage Production
, 1970 A field experiment was accomplished to establish appropriate plant spacing for summer season cabbage production in the rain fed condition of the high hills of eastern Nepal. The experiment was conducted during the summer of 1997, 1998 and 1999.
Purushottam P Khatiwada
core +1 more source
Maintenance of Air in Intercellular Spaces of Plants [PDF]
Plant Physiology, 1983 Although air-filled intercellular spaces are necessary and ubiquitous in higher plants, little attention has been paid to the possible mechanisms by which these spaces are kept from being flooded. The most likely mechanism is that the living plant cell may maintain a hydrophobic monolayer on the surfaces of adjacent intercellular spaces.
openaire +2 more sources