CRISPR-TSKO : a technique for efficient mutagenesis in specific cell types, tissues, or organs in Arabidopsis [PDF]
Detailed functional analyses of many fundamentally important plant genes via conventional loss-of-function approaches are impeded by the severe pleiotropic phenotypes resulting from these losses.
Andrade Buono, Rafael +9 more
core +1 more source
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Anatomical Alterations in Plant Tissues Induced by Plant-Parasitic Nematodes
Plant-parasitic nematodes (PPNs) interact with plants in different ways, for example, through subtle feeding behavior, migrating destructively through infected tissues, or acting as virus-vectors for nepoviruses.
Juan E. Palomares-Rius +4 more
doaj +1 more source
Temporal changes in carboxylate content of ryegrass with stepwise change in nutrition [PDF]
A detailed scheme of carboxylate formation and retention by plant tissues as a result of ion uptake and utilization is given. By means of discontinuities in the supply with nutrient ions, carboxylate retention by the tissues of perennial ryegrass was ...
Dijkshoorn, W. +2 more
core +2 more sources
Mathematical Modelling of Auxin Transport in Plant Tissues:Flux Meets Signalling and Growth [PDF]
Plant hormone auxin has critical roles in plant growth, dependent on its heterogeneous distribution in plant tissues. Exactly how auxin transport and developmental processes such as growth coordinate to achieve the precise patterns of auxin observed ...
Allen, Henry R., Ptashnyk, Mariya
core +3 more sources
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Processus de croissance et d'organogenese chez le pommier cv Golden Delicious [PDF]
Growth and organogenesis processes in apple tree cv Golden Delicious. This work aims to focus on the organogenetic activity, growth and histological processes in the shoot apical meristem of apple cv Golden Delicious.
Mehri H., Crabbe J.
doaj
Susceptibility, diffusion and relaxation contrast in NMR microscopy at high resolution : a thesis presented in partial fulfilment of the requirement for the degree of Master of Science in physics at Massey University [PDF]
An integrated approach to the functional NMR imaging of plant tissue at moderately-high transverse resolution (23 µm) was undertaken. Attention was paid to all the possible commonly-known influences, such as sources of nuclear spin relaxation or of ...
Forde, Lucy Catherine
core
Tissue specific analysis reveals a differential organization and regulation of both ethylene biosynthesis and E8 during climacteric ripening of tomato [PDF]
Background: Solanum lycopersicum or tomato is extensively studied with respect to the ethylene metabolism during climacteric ripening, focusing almost exclusively on fruit pericarp. In this work the ethylene biosynthesis pathway was examined in all major
Bulens, Inge +14 more
core +2 more sources
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source

