Results 221 to 230 of about 77,880 (309)

Artificial intelligence‐based statistical modeling delineates architectural distortion in focal cortical dysplasia

open access: yesBrain Pathology, EarlyView.
Histopathological identification of subtle cortical architectural abnormalities in focal cortical dysplasia (FCD) resections remains challenging. We investigated if artificial intelligence (AI)‐based morphometric and spatial analysis of NeuN‐stained cortical sections could detect neuronal architectural disorganization in epilepsy resections, including ...
Andrew Cannon   +9 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Climate shocks, coping strategies, and household resilience: Evidence from a three‐wave panel in Malawi

open access: yesContemporary Economic Policy, EarlyView.
Abstract Climate shocks threaten rural livelihoods in Malawi, yet households adopt diverse coping strategies to mitigate welfare losses. Using three‐wave Living Standards Measurement Study–Integrated Surveys on Agriculture panel data (2013–2019) and household fixed‐effects models, this study examines how climate shocks affect food security and ...
Suyeon Ro, Jongwook Lee
wiley   +1 more source

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