Results 131 to 140 of about 14,625 (259)

Femtolitre Volume cryoEM Sample Preparation Using a Force‐Sensitive Microfluidic Cantilever

Advanced Materials Technologies, EarlyView.
Cryogenic electron microscopy enables structural imaging of biological molecules, but current methods lack targeted extraction of subcellular content for direct vitrification. This study introduces a force‐sensitive microfluidic cantilever pipette that aspirates and dispenses femtolitre volumes from individual cells onto electron microscopy grids.
Vijayendra Shastri, Joachim Pronk, Eleonoor Verlinden, Daniel Torres González, Edin Sarajlic, Paul Laeven, Wiel Evers, Patrick Frederix, Urs Staufer, Arjen J. Jakobi, Murali Krishna Ghatkesar, Andreas Engel   +11 more
wiley   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic

Advanced Sensor Research, EarlyView.
This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin, Scott G. Harroun, Michel Meunier   +2 more
wiley   +1 more source

Digital Bioassays on the Slipchip Microfluidic Devices

Advanced Sensor Research, EarlyView.
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo, Ziqing Yu, Weiyuan Lyu, Yang Luo, Lei Xu, Feng Shen   +5 more
wiley   +1 more source

Advancements in Plant Diagnostic and Sensing Technologies

Advanced Sensor Research, EarlyView.
This review explores plant diagnostic and sensing technologies, highlighting key traits, structures, and metabolites. It covers conventional methods like leaf light reflectance and fluorescence, as well as advanced optical techniques such as Fourier transform infrared spectroscopy and Raman spectroscopy. The integration of machine learning, statistical
Shalini Krishnamoorthi, Sally Shuxian Koh, Mervin Chun‐Yi Ang, Mark Ju Teng Teo, Randall Ang Jie, U. S. Dinish, Michael S. Strano, Daisuke Urano   +7 more
wiley   +1 more source

Loss-of-Function of Two PD-Associated Proteins Confers Resistance to Rice Stripe Virus. [PDF]

Mol Plant Pathol
Lu H, Ge P, Ma Y, Lin F, Jing D, Zhou T, Cui F.   +6 more
europepmc   +1 more source

Label‐Free, Sensitive, and Direct Detection of Cardiac Troponin Biomarkers Using Frequency‐Locked Microring Resonators

Advanced Sensor Research, EarlyView.
A deployable, chip‐integrated approach to the detection of heart attack biomarkers is demonstrated using silicon photonic microring resonators combined with microfluidics. By applying the Pound–Drever–Hall frequency locking technique, sensor signals are measured with improved signal‐to‐noise ratio, applying this to real‐time, selective readouts.
Evan Diamandikos, Tetsuya Shimogaki, Crispin Szydzik, Peter Thurgood, Luke H. Broadley, Sonya Palmer, Guanghui Ren, Thach G. Nguyen, Cesar S. Huertas, Arnan Mitchell   +9 more
wiley   +1 more source

Viral tropism in plants, reproductive tissues, and seeds. [PDF]

Arch Microbiol
Núñez-Muñoz LA, Calderón-Pérez B, Ruiz-Medrano R, Xoconostle-Cázares B, de la Torre-Almaraz R.   +4 more
europepmc   +1 more source

Compact Multichannel Plasmonic Device for Rapid and Versatile Inflammatory Biomarker Analysis

Advanced Sensor Research, EarlyView.
A multichannel plasmonic biosensor has been developed for the simultaneous detection of up to four inflammatory biomarkers relevant to sepsis diagnostics. Its performance has been optimized, and analytical validation has been conducted for the detection in diluted serum, highlighting its potential for clinical applications.
Juliana Fátima Giarola, Patricia Ramirez‐Priego, M.‐Carmen Estevez, Laura M. Lechuga   +3 more
wiley   +1 more source

The genomic region matters when synthesizing dsRNA for plant virus suppression via RNAi. [PDF]

Virol J
Barroso K, Milagres J, Tracton T, Shidore T, Muthuramalingam R, El-Tanbouly R, Ambrósio M, da Silva W.   +7 more
europepmc   +1 more source