Results 201 to 210 of about 14,625 (259)

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

Advanced Science, EarlyView.
Zhan et al. demonstrate the vital role of NAT10‐catalyzed ac4C modification in regulating autophagy‐associated lysosomal acidification. They uncover the clinical and biological significance of ATP6V0E1, an important v‐ATPase assembly subunit, in tumor metastasis, particularly in the malignant progression of ESCC.
Yu‐Juan Zhan, Chun‐Miao Deng, Lin Tang, Shu‐Jun Li, Tao‐Yang Xu, Xian Wei, Xin‐Yi Zhang, Can‐Can Zheng, Li Deng, Cui Shao, Zhong‐Min Ouyang, Alfred King‐Yin Lam, Rong Zhang, Jun Liu, Xing‐Yuan Shi, Zhen‐Yu Pan, Wei Dai, Ming‐Liang He, Simon Law, Xu Li, Xiao‐Bing Chen, Cheng Zhou, Bin Li, Wen‐Wen Xu   +23 more
wiley   +1 more source

Receptor-like kinases BIR1 and BIR3 modulate antiviral resistance by different mechanisms. [PDF]

New Phytol
Robinson C, Guzmán-Benito I, Sede AR, Elvira-González L, Hua C, Ciska M, Nürnberger T, Heinlein M, Llave C.   +8 more
europepmc   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

Phytohormones and emerging plant growth regulators in tailoring plant immunity against viral infections. [PDF]

Physiol Plant
Shukla K, Nikita, Ahmad A, Noorani MS, Gupta R.   +4 more
europepmc   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Binding Specificity and Oligomerization of TSWV N Protein in the Western Flower Thrips, <i>Frankliniella occidentalis</i>. [PDF]

Viruses
Khan F, Abdisa E, Shahmohammadi N, Kim Y.   +3 more
europepmc   +1 more source

Ultrasound‐Mediated Biotransfection of Engineered Bone Marrow Mesenchymal Stem Cells in Treated Bone Defects through Intracellular Cavitation

Advanced Science, EarlyView.
Ultrasound‐mediated biotransfection through intracellular cavitation increases plasmid nuclear translocation and gene transfection efficiency by 284.7% and 131.6% in engineered bone marrow mesenchymal stem cells (BMSCs) compared to traditional ultrasound‐targeted microbubble destruction techniques. The maintained bone morphogenetic protein 2 expression
Zhili Xu, Huijuan Xin, Yu Wang, Renhao Xu, Yanni He, Meijun Zhou, Zhengqiang Yuan, Hongmei Liu   +7 more
wiley   +1 more source

Identification of host specificity determinants in brome mosaic virus for rice infection. [PDF]

Virus Res
Zhang Y, Kaido M, Mine A, Takano Y, Mise K.   +4 more
europepmc   +1 more source

A Myelin Debris Cleaner for Spinal Cord Injury Recovery: Polycaprolactone / Cell Membrane Assembled Scaffolds

Advanced Science, EarlyView.
pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou, Tao Xu, Yiyan Zhou, Nuo Chen, Zhengchao Wu, Zongze Yang, Changwei Yang, Xiaoqing Chen   +7 more
wiley   +1 more source

Development of a pod pepper vein yellows virus-based expression vector for the production of heterologous protein or virus like particles in Nicotiana benthamiana. [PDF]

Virus Res
Wang L, Zhang G, Bu S, Lin Z, Wu J, Yan F, Peng J.   +6 more
europepmc   +1 more source