Results 221 to 230 of about 55,656 (302)

Sugarcane streak mosaic virus P1 protein targets the BES1 transcription factor to subvert DAMP-triggered immunity in plant. [PDF]

Sci Adv
He Z, Deng X, Chen H, Xu X, Tang M, Hua Y, Qin L, Feng C, Gu T, Zhuang X, Xu K, Roussin-Léveillée C, Moffett P, Zhang K.   +13 more
europepmc   +1 more source

“More” Artificial mRNAs: Beyond the Art of Nature

Advanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui, Minami Fukui, Hirohisa Ohno, Hirohide Saito   +3 more
wiley   +1 more source

Plant virus seed transmission: AGO5-mediated defense and viral counter-defense. [PDF]

Front Plant Sci
Lezzhov AA, Atabekova AK, Chergintsev DA, Lazareva EA, Solovyev AG.   +4 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

The PSRP2/4 Proteins Promote Viral Infection by Interacting with the VPg Protein of TuMV. [PDF]

Plants (Basel)
Lyu S, Lu W, Zhang C, Wang W, Yuan M, E L, Liu T, Deng S.   +7 more
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Comparative transcriptomic dynamics reveal molecular responses of susceptible and resistant Triticum aestivum genotypes to wheat stripe mosaic virus. [PDF]

Sci Rep
Nascimento SC, Pereira FS, Silva VIA, Santi VM, Mendes GC, Lau D, Junior AN, Giachetto PF, Matsumura EE, Silva FN.   +9 more
europepmc   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Lettuce Big-Vein Associated Virus ORF3 Encodes a Functional 30K Movement Protein. [PDF]

Mol Plant Pathol
Schravesande WEW, Cligge MV, Frijters R, Verhage A, van den Burg HA.   +4 more
europepmc   +1 more source

Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model

Advanced Science, EarlyView.
Understanding protein sequence–function relationships remains challenging due to poorly defined motifs and limited residue‐level annotations. An annotation‐agnostic framework is introduced that segments protein sequences into “protein words” using attention patterns from protein language models.
Hedi Chen, Jingrui Zhong, Xiaochun Zhang, Jingke Chen, Lin Guo, Xiaoliang Xiong, Xiaonan Zhang, Xiangyu Liu, Bailong Xiao, Boxue Tian   +9 more
wiley   +1 more source