Results 61 to 70 of about 298 (198)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Family Level Phylogenies Reveal Relationships of Plant Viruses within the Order Bunyavirales

Viruses, 2020
Bunyavirales are negative-sense segmented RNA viruses infecting arthropods, protozoans, plants, and animals. This study examines the phylogenetic relationships of plant viruses within this order, many of which are recently classified species ...
Venura Herath, Gustavo Romay, Cesar D. Urrutia, Jeanmarie Verchot   +3 more
doaj   +1 more source

Tubule-guided cell-to-cell movement of a plant virus requires class XI myosin motors. [PDF]

PLoS Pathogens, 2011
Cell-to-cell movement of plant viruses occurs via plasmodesmata (PD), organelles that evolved to facilitate intercellular communications. Viral movement proteins (MP) modify PD to allow passage of the virus particles or nucleoproteins.
Khalid Amari, Alexander Lerich, Corinne Schmitt-Keichinger, Valerian V Dolja, Christophe Ritzenthaler   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Exploring the Diversity of Mechanisms Associated With Plant Tolerance to Virus Infection

Frontiers in Plant Science, 2018
Tolerance is defined as an interaction in which viruses accumulate to some degree without causing significant loss of vigor or fitness to their hosts. Tolerance can be described as a stable equilibrium between the virus and its host, an interaction in ...
Dinesh Babu Paudel, Hélène Sanfaçon
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Viral Systemic Movement Is Enhanced by Alteration of a Structural Phloem Protein by the Insect Vector

Advanced Science
The ability to access and exploit the vascular system is essential for viral systemic spread within plant hosts. Insect‐borne viruses can be released from the vector's stylets into plant phloem together with saliva components that facilitate viral ...
Huijuan Guo, Qingyun Shi, Xiaoyu Ling, Yuting Wu, Lin He, Danyang Li, Keyan Zhu‐Salzman, Yucheng Sun   +7 more
doaj   +1 more source

Beet necrotic yellow vein virus accumulates inside resting spores and zoosporangia of its vector Polymyxa betae BNYVV infects P. betae

Virology Journal, 2007
Background Plasmodiophorids and chytrids are zoosporic parasites of algae and land plant and are distributed worldwide. There are 35 species belonging to the order Plasmodiophorales and three species, Polymyxa betae, P.
Payton Mark, Rush Charles M, Lubicz Jeanmarie, Colberg Terry   +3 more
doaj   +1 more source

Patellins 3 and 6, two members of the Plant Patellin family, interact with the movement protein of Alfalfa mosaic virus and interfere with viral movement.

Molecular plant pathology, 2014
[EN] Movement proteins (MPs) encoded by plant viruses interact with host proteins to facilitate or interfere with intra- and/or intercellular viral movement. Using yeast two-hybrid and bimolecular fluorescence complementation assays, we herein present invivo evidence for the interaction between Alfalfa mosaic virus (AMV) MP and Arabidopsis Patellin 3 ...
Peiró Morell, Ana, Izquierdo García, Ana Cristina, Sánchez-Navarro, Jesús-Ángel, Pallás Benet, Vicente, Mulet, José Miguel, APARICIO HERRERO, FREDERIC   +5 more
openaire   +3 more sources