Results 131 to 140 of about 9,959,581 (262)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Arizona department of water resources: Securing Arizona\u27s water future

open access: yes, 1998
The Arizona Department of Water Resources works to secure long-term dependable water supplies for Arizona\u27s communities. The Department: administers and enforces Arizona\u27s groundwater code, and surface water rights laws (except those related to ...
Arizona Department of Water Resources
core  

Development of a thermal sensor for probing small volumes [PDF]

open access: yes, 2012
This thesis presents the design, fabrication and characterisation of a thermal micro-sensor capable of operating on small scale samples. It was initially characterised by measuring the thermal conductivity of 100 μl liquid droplets and thin materials ...
ATHERTON, JOSEPH,JAMES
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Report (Texas Water Development Board)

open access: yes, 2004
A guide on the practices, techniques, programs, and technologies that will protect water resources, reduce the consumption of water, reduce the loss or waste of water, improve the efficiency in the use of water, and increase the recycling and reuse of ...
Texas Water Development Board
core  

A multi-tool approach for assessing fruit growth, production and plant water status of a pear orchard

open access: yes, 2018
Only very little is published on simple tools for monitoring seasonal information relating plant water status to fruit growth/yield in horticultural crops.
P. Losciale   +15 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The Water Status Measurements Associated with Plant Growth

open access: yesEnvironment Control in Biology, 2007
The process of cell elongation from the viewpoint of plant-water relations and the effect of excision in the zone of elongation on changes in the water status are discussed. The excision effect on changes in water potential was evaluated after measuring turgor before excision and after excision in growing tulip tepals, and it was found that the size of
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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