Results 181 to 190 of about 127,017 (298)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

A Case Report - K Wire as Guide in Endoscopic Plantar Fascia Release for Beginners. [PDF]

J Orthop Case Rep
Yadoji HK, Gottemukkala AR, Juvvadi V, Kanuri H.   +3 more
europepmc   +1 more source

Plantar Warts

International Journal of Clinical Practice, 1957
openaire   +2 more sources

Anesthetic Management of Cervicomedullary Decompression in a Child With Down Syndrome: A Case Report

Pediatric Discovery, EarlyView.
Muhammad Saad, Marium Amjad
wiley   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Speed-related increases in plantar tissue stress without affected-side laterality in individuals with unilateral shoulder dislocation. [PDF]

Front Public Health
Lu Z, Xiao L, Liang P, Chen M, Guo L, Ma L, Li D.   +6 more
europepmc   +1 more source

Two Novel ACTC1 Variants Cause Arthrogryposis Multiplex Congenita

Clinical Genetics, EarlyView.
We report on two individuals with arthrogryposis multiplex congenita who were heterozygous for ACTC1 missense variants (NM_005159.5; c.325G>A, p.Glu109Lys and c.650A>C, p.Lys217Thr) and provide a characterization of these variants through in vitro studies.
Lauren Kerr, Pierre Moffatt, Lauren Hyer, Sarah Nossov, Noémi Dahan‐Oliel, Frank Rauch   +5 more
wiley   +1 more source

Enhanced Melan‐A Red Chromogen Labeling in Melanoma Compared to Nevus Cells: A Diagnostic Aid in Dual Multiplex Immunohistochemistry With Ki67

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Distinguishing melanoma cells from nevus cells remains a diagnostic challenge, particularly in cases where melanoma exhibits nevoid morphology or nevus cells display atypical or epithelioid features. Accurate identification is essential for proper measurement of Breslow depth in melanomas arising in association with nevi and for ...
Peter N. Kundert, Elsayed H. Ibrahim, Victor G. Prieto, Phyu P. Aung   +3 more
wiley   +1 more source

Efficacy of Static Stretching Along With Frozen Tennis Ball Exercises in Individuals With Plantar Fasciitis. [PDF]

Cureus
Shinde VV, Patil PR.
europepmc   +1 more source

Eruptive Acral Melanocytic Lesions Associated With Capecitabine

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Eruptive nevi and lentigines have been reported to occur in the setting of immunosuppression, which may be medication‐induced. The associated histopathologic findings have not been well described in the literature. Herein, we report the case of a woman in her 60s who had been receiving chemotherapy treatment with capecitabine, a prodrug of 5 ...
Madison Smith, Annie Jin, Jonathan A. Miles, Rosalie Elenitsas, Danielle M. DeHoratius, Emily Y. Chu   +5 more
wiley   +1 more source