Results 171 to 180 of about 2,504,099 (239)

Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang   +2 more
wiley   +1 more source

Low‐threshold cutaneous mechanoreceptors on the foot sole have enhanced sensitivity when skin temperature is elevated

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of microneurography recordings used to examine the effects of local skin heating on cutaneous mechanoreceptor responses in the human foot (left panel). A microelectrode inserted into a peripheral nerve records single‐unit activity from tactile afferent fibres while controlled mechanical stimuli are applied ...
Erika E. Howe   +4 more
wiley   +1 more source

Effects of a Passive Lower-Limb Exoskeleton on Plantar Pressure Distribution and Postural Stability During Prolonged Occupational Standing: A Pilot Ergonomic Study. [PDF]

open access: yesHealthcare (Basel)
Achim Borza BA   +5 more
europepmc   +1 more source

Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an optogenetic gain‐of‐function manipulation to investigate how sensory signals from two subtypes of Aβ low threshold mechanoreceptors (LTMRs) contribute to the cortical representation of touch. CatCh, a sensitive and fast channelrhodopsin variant, enables pulsed‐light generation of high‐frequency action potential trains ...
Wanyi Liu   +2 more
wiley   +1 more source

Association of Musculoskeletal Pain With Foot Type, Plantar Pressure, Physical Activity, Psychosocial Factors, and Daily Living Habits Among Adolescents. [PDF]

open access: yesClin Med Insights Arthritis Musculoskelet Disord
Zhang Y   +11 more
europepmc   +1 more source

Cutaneous‐only hypersensitivity reaction presumed due to intravenous administration of atracurium in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary There are limited case reports of hypersensitivity reactions to neuromuscular blocking agents (NMBAs) in veterinary species, and none describe cutaneous‐only signs. This case report describes a Grade 1 cutaneous‐only hypersensitivity reaction to atracurium in a 7‐year‐old dog undergoing general anaesthesia for cataract surgery with bilateral ...
Kar Yee Phoon, Rob Ward
wiley   +1 more source

AI-based wearable system for fall risk prediction in older adults using sEMG and plantar pressure data. [PDF]

open access: yesFront Bioeng Biotechnol
Ma X   +9 more
europepmc   +1 more source

Histopathologic Analysis of the Morpho‐Functional Zones of the Human Acetabular Labrum

open access: yesClinical Anatomy, Volume 39, Issue 7, Page 787-800, October 2026.
ABSTRACT The structural and functional adaptation of soft tissues to mechanical load controls their ability to withstand injury and influences their capacity for healing. Similar to the knee meniscus, the acetabular labrum exhibits zonal differences in mechanical load distribution, resulting in distinct regions with unique structural and functional ...
Abdulaziz A. Alomiery   +4 more
wiley   +1 more source

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