Results 201 to 210 of about 2,504,099 (239)

Cannabinoid CB1 allosteric ligands suppress inflammatory pain in male mice without tolerance, motor impairment, memory deficits or respiratory depression

British Journal of Pharmacology, Volume 183, Issue 20, Page 6132-6153, October 2026.
Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon, Sumanta Garai, Ganesh A. Thakur, Andrea G. Hohmann   +3 more
wiley   +1 more source

Therapeutic Effect of Schroth Method on Plantar Pressure and Related Muscle Imbalance in Children and Adolescent With Idiopathic Scoliosis. [PDF]

Arch Rehabil Res Clin Transl
Shi Y, Huang X, Shu Z, Pang Q, Tu F.
europepmc   +1 more source

Inhibition of leucine‐rich kinase 2 (LRRK2) promotes peripheral axon regeneration via phosphorylation‐network remodelling

British Journal of Pharmacology, Volume 183, Issue 20, Page 6199-6224, October 2026.
Background and Purpose In contrast to neurons in the central nervous system, neurons in the peripheral nervous system can regenerate axons after injury via activation of a pro‐regenerative transcriptional programme. Pathogenic mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, and several small ...
Eun‐Hae Jang, Eun Mo Yang, Gil Song, Seung Min Park, Harryn Choi, Jaeyong Kim, Chanil Kim, Yunho Gim, Hyuk‐Joo Jeon, Yewon Cho, Jong Bae Park, Eun‐Mi Hur   +11 more
wiley   +1 more source

A Wearable Multi-Modal Measurement System with Self-Developed IMUs and Plantar Pressure Sensors for Real-Time Gait Recognition. [PDF]

Micromachines (Basel)
Li X, Gao Y, Chen G, Zhang M, Liao J, Wang Z, Sun J.   +6 more
europepmc   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 10, Page 1648-1661, October 2026.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

Plantar pressure distribution can be used to identify sarcopenia in maintenance hemodialysis patients. [PDF]

Sci Rep
Yang Y, Liao H, Chen Y, Qiu Y, Yan F, Fu P, Yue J, Chen Y, Yuan H.   +8 more
europepmc   +1 more source

Postcranial anatomy of the Miocene hippopotamoids of Toros‐Menalla, Chad

Journal of Anatomy, Volume 249, Issue 4, Page 924-949, October 2026.
We establish a framework for the identification of postcranial remains in hippopotamoids by describing and comparing for the first time two late Miocene hippopotamoids from Toros‐Menalla, Chad (Hexaprotodon garyam, an early hippopotamid, and Libycosaurus bahri, the last African anthracothere) with the common hippopotamus.
Lorenzo Scribano, Fabrice Lihoreau, Alexandra Houssaye, Clarisse Nekoulnang Djetounako, Jean‐Renaud Boisserie   +4 more
wiley   +1 more source

Plantar Pressure Distribution in Charcot-Marie-Tooth Disease: A Systematic Review. [PDF]

Sensors (Basel)
Arceri A, Mazzotti A, Sgubbi F, Zielli SO, Langone L, Di Paola G, Brognara L, Faldini C.   +7 more
europepmc   +1 more source

Functional morphology of trabecular bone in the calcaneus of African apes

Journal of Anatomy, Volume 249, Issue 4, Page 883-898, October 2026.
Pan exhibits significantly higher calcaneal tuberosity trabecular thickness (Tb.Th) and bone volume fraction (BV/TV) than Gorilla, potentially reflecting higher triceps surae forces for vertical climbing. Both taxa have significantly higher Tb.Th and BV/TV in the anterior calcaneus; the difference is exaggerated in Gorilla, potentially reflecting ...
Christine M. Harper, Biren A. Patel
wiley   +1 more source