Results 151 to 160 of about 30,001 (308)

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

open access: yesAdvanced Science, EarlyView.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu   +5 more
wiley   +1 more source

Assessment of mining activities with respect to the environmental protection [PDF]

open access: yes, 2017
This paper deals with the impact of mining on the environment. Coal mining is still among the most widespread and most intense mining activity, which disturbs the landscape around us bringing regional environmental, economic and aesthetic problems ...
Dirner, Vojtech   +3 more
core  

Skin‐Inspired Design of Self‐Healing Coatings Integrating Interface‐Liquid Repellency and Corrosion Resistance

open access: yesAdvanced Science, EarlyView.
A skin‐inspired multilayered coating system is developed to integrate multiple, often conflicting, functions of self‐healing capability, strong liquid repellency, long‐term corrosion resistance, and robust adhesion, to tackle diverse challenges in engineering services.
Bingzhi Li   +8 more
wiley   +1 more source

Effect of Humic Acid and Cattle Manure on Stomatal Conductance, Photosynthesis, and Growth Variables of White Mulberry Seedlings in the Nursery Condition [PDF]

open access: yesبوم‌شناسی جنگل‌های ایران
Extended Abstract Background: In contemporary times, the increasing population growth in large urban areas, industrial development in these cities, and the need for expanding urban green spaces and green belts have drawn the attention of managers to the ...
Davoud Kartoolinejad, Iman Sahebalam
doaj  

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

open access: yesAdvanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu   +6 more
wiley   +1 more source

Impacts of FAVR Restriction Elimination on the Dry Bean Industry in the Upper Midwest [PDF]

open access: yes
Farm Policy, Planting Flexibility, Agricultural and Food Policy, Q18,
Thornsbury, Suzanne
core   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong   +14 more
wiley   +1 more source

Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design

open access: yesAdvanced Science, EarlyView.
Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao   +4 more
wiley   +1 more source

Sugar‐Armored Pesticides: Self‐Assembled System for Enhanced Foliar Adhesion and Sustained Delivery of Hydrophobic Antimicrobials Against Bacterial Diseases

open access: yesAdvanced Science, EarlyView.
This study develops a sugar‐armored, self‐assembled pesticide delivery system that enhances foliar adhesion, provides sustained release, effectively disrupts biofilms, and demonstrates superior bactericidal activity for improved disease control.
Jinghan Yang   +3 more
wiley   +1 more source

Toward Complete CO2 Electroconversion: Status, Challenges, and Perspectives

open access: yesAdvanced Energy Materials, EarlyView.
Electrocatalytic CO2 reduction and CO2 batteries face challenges in achieving complete CO2 conversion with high conversion rates and Faradaic efficiency simultaneously. Existing systems compromise one for the other with incomplete CO2 conversion and inefficiencies, hindering practical applications. This perspective highlights state‐of‐the‐art progress,
Changfan Xu   +5 more
wiley   +1 more source

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