Results 151 to 160 of about 9,139,223 (407)
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Robust PI Controller Design Satisfying Gain and Phase Margin Constraints [PDF]
This paper presents a control design algorithm for determining PI-type controllers satisfying specifications on gain margin, phase margin, and an upper bound on the (complementary) sensitivity for a finite set of plants.
Nagurka, Mark L., Yaniv, O.
core +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Two phase continuous digestion of solid manure on-farm: design, mass and nutrient balance [PDF]
During the last decade some so called ‘dry fermentation’ prototype plants were developed for anaerobic digestion of organic material containing 15-50 % total solids.
Evers, Lars+5 more
core
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Extended aeration : a comparative study between prefabricated reinforced fiberglass and concrete cast in-situ plants [PDF]
The choice of wastewater treatment plants for any application depends on the quality of raw sewage, the required quality of treated water and the economics resources available to pay for both capital cost and operating cost of the treatment plants.
Abdul Razik, Mohd. Shukri
core