Results 241 to 250 of about 2,613,867 (300)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Esca disease triggers local transcriptomic response and DNA methylation changes in grapevine. [PDF]

open access: yesJ Exp Bot
Berger MMJ   +6 more
europepmc   +1 more source

Investigation of changes in the profile of fatty acids and growth traits in response to waterlogging/flooding stress. [PDF]

open access: yesPLoS One
Gul MZ   +8 more
europepmc   +1 more source

Dual regulation of the receptor-like kinase BIR1 involves site-directed transcript cleavage and 5'-leader-mediated translational control. [PDF]

open access: yesPLoS Pathog
Guzmán-Benito I   +8 more
europepmc   +1 more source

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