Results 71 to 80 of about 1,015,579 (269)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A carbon dot toolbox for managing biotic and abiotic stresses in crop production systems
The productivity of global crop production is under threat caused by various biotic and abiotic adverse conditions, such as plant diseases and pests, which are responsible for 20%–40% of global crop losses estimated at a value of USD 220 billion, and can
Muhammad U. Zia +5 more
doaj +1 more source
Nanoparticles as Potential Eustressors in Plants
In recent years, the acceleration of climate change and the growing demand for higher-quality food to meet the needs of an expanding population have become pressing challenges.
Susana Rodríguez-Jurado +4 more
doaj +1 more source
The Effects of Lead Species and Growth Time on Accumulation of Lead in Chinese Cabbage
A major pathway for heavy metal exposure in contaminated areas is via consumption of locally produced food. This study investigated the accumulation of lead in Chinese cabbage grown in contaminated soils and estimated the weekly dietary intake ...
Megan Corley, Samuel Mutiti
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Molecular Evolution of Cu Transporters and Transcription Factors in Plant Response to Copper Stress
Copper (Cu) is an essential micronutrient for plants, playing a crucial role in various physiological and molecular processes. Excess Cu induces oxidative stress and disrupts cellular functions, while Cu deficiency causes chlorosis and poor pollen ...
Haiyang Tang +12 more
doaj +1 more source
Biogenic speleothems: an overview. [PDF]
The idea that speleothems may be somehow influenced by living organisms is rather old, but specific studies have only started in the last few decades and presently there are only a couple of systematic papers on this topic. The role of micro-organisms is
Forti Paolo
doaj
The Upper Famennian Ketleri Formation of Latvia: new data on the fauna and flora from tide-dominated delta deposits in a seasonal climate [PDF]
Combined sedimentological and palaeontological studies of the vertebrate fossil-bearing deposits of the Upper Devonian, Upper Famennian Ketleri Formation have provided new data on the sedimentary environment of the deposits, as well as on taxonomic and ...
Ervīns Lukševičs +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

