Results 51 to 60 of about 81,113,489 (300)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Risk assessment and reduction options for Ceratocystis platani in the EU
EFSA Journal, 2016 Following a request from the European Commission, the EFSA Plant Health (PLH) Panel performed a risk assessment for Ceratocystis platani in the EU with the aim to assess the effectiveness of risk reduction options (RROs) on the basis of the mechanisms of
EFSA Panel on Plant Health (PLH) +22 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Acta Scientiarum. Agronomy, 2021 The objective was to evaluate the forage yield and structural responses of spineless cactus ‘Orelha de Elefante Mexicana’ (OEM) (Opuntia stricta (Haw.) Haw) at different planting densities.
Juliana de Souza Pereira +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2021 The cocoa tree, a crop highly prized in the world for its beans, is one of pillars of the Ivorian economy. However, it is confronted with numerous constraints including climatic disturbances which disturb the cropping calendar. The aim of this work is to
N'guessan Walet Pierre +6 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
EFFECT OF PLANTING CONDITIONS AND PLANTING DATES ON VEGETATIVE GROWTH, FLOWERING, BULBS PRODUCTION AND CHEMICAL CONSTITUENTS OF IRIS TINGITANA CV. WEDGEWOOD PLANTS [PDF]
, 2019 The present experiment was consummated throughout two successive seasons (2016/2017 and 2017/2018) at the nursery of Horticulture Research Institute, Agricultural Research Center, Giza, Egypt with the aim to solve one of the most important problem facing
Z Abdel-Said
core +2 more sources
Research on the Promotion and Application of Understory Ground Cover Plants in Shanghai Parks [PDF]
园林The study focuses on understory ground cover plants in Shanghai parks, where sample plots were randomly selected from understory zones with aesthetically pleasing landscapes.
YAN Zi, LI Mengping, ZHANG Shoufeng
doaj +1 more source