Results 301 to 310 of about 503,732 (331)
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Agents that stabilise atherosclerotic plaque
Expert Opinion on Investigational Drugs, 2003The concept of plaque stabilisation was developed to explain how medications could decrease adverse coronary events without a substantial reduction in the regression of atherosclerosis. With this concept, a comprehensive view of atherosclerosis is now appreciated.
Jun R Chiong, Alan B Miller
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Rapid inhibition of atherosclerotic plaque progression by sonodynamic therapy
Cardiovascular Research, 2018Aims Currently, efficient regimens to reverse atherosclerotic plaques are not available in the clinic. Herein, we present sonodynamic therapy (SDT) as a novel methodology to rapidly inhibit progression of atherosclerotic plaques. Methods and results In
Xin Sun +29 more
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2015
Over the past decade, significant strides have been made in advanced non-invasive cardiac imaging. Technological advances in both hardware and software applications have made direct visualization of atherosclerotic plaque a reality. These advances have come at a crucial time, and help to fill a gap in contemporary diagnostic modalities, which have ...
P. Singh, A. Tawakol
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Over the past decade, significant strides have been made in advanced non-invasive cardiac imaging. Technological advances in both hardware and software applications have made direct visualization of atherosclerotic plaque a reality. These advances have come at a crucial time, and help to fill a gap in contemporary diagnostic modalities, which have ...
P. Singh, A. Tawakol
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MR imaging of atherosclerotic plaque
Radiologic Clinics of North America, 2002MRI is a powerful noninvasive imaging tool with high spatial resolution that continues to prove its value in determining atherosclerotic plaque size, volume, and tissue components. Multispectral MRI sequences have been validated to characterize atherosclerotic plaque components in animals; they have recently been applied to human aorta and carotid ...
Christopher M. Kramer, C. Joon Choi
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Is regression of atherosclerotic plaque possible?
Clínica e Investigación en Arteriosclerosis (English Edition), 2017As it is well-known, a thrombus evolving into a disrupted/eroded atherosclerotic plaque causes most acute coronary syndromes. Plaque stabilization via reduction of the lipid core and/or thickening of the fibrous cap is one of the possible mechanisms accounted for the clinical benefits displayed by different anti-atherosclerotic strategies.
José A. Páramo, Fernando Civeira
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Atherosclerotic plaque assessment by NMR
Magnetic Resonance Materials in Physics, Biology and Medicine, 1998Developing imaging technologies capable of identifying unstable atheromatous plaques in vivo is a major issue of clinical cardiovascular research. These techniques would allow an earlier surgical or medical therapy before acute ischemic syndromes [1]. Plaque stability and its counterpart i.e.
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Impact of Statins on Atherosclerotic Plaque
Future Cardiology, 2007Lowering levels of low-density lipoprotein cholesterol with inhibitors of 3-hydroxy-methylglutaryl coenzyme A reductase (statins) has a profound impact on cardiovascular event rates. The degree of benefit is proportional to the extent of low-density lipoprotein cholesterol lowering achieved. In addition to lowering levels of atherogenic lipids, statins
Adnan K. Chhatriwalla +2 more
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Evaluation of Coronary Atherosclerotic Plaques
Cardiology Clinics, 2009In many patients, unheralded myocardial infarction associated with a mortality of approximately 20% is the first manifestation of coronary artery disease. Approximately 40% of the population is considered to have a moderate midterm risk of 10% to 20%. Any of the stratification schemes suffers from a lack of accuracy to correctly determine the risk, and
Christoph R. Becker, Tobias Saam
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Progression and regression of the atherosclerotic plaque
European Heart Journal, 1995In animals in which atherosclerosis was induced experimentally (by a high cholesterol diet) regression of the atherosclerotic lesion was demonstrated after serum cholesterol was reduced by cholesterol- lowering drugs or a low-fat diet. Whether regression of advanced coronary arterly lesions also takes place in humans after a similar intervention ...
P. J. De Feyter +2 more
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The vulnerable atherosclerotic plaque
Emerging Drugs, 1998Several major clinical trials reported over the past three years have shown that lowering of plasma cholesterol with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, has led to a substantial reduction in clinical events such as heart attack, stroke or death. These striking and encouraging observations were not predicted
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