Results 241 to 250 of about 1,105,082 (410)

Periodontal Diseases in Children and Adolescents

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2008
Periodontal diseases are the most common chronic conditions affecting the human race. Recently, increased attention has been given to these diseases because they were found to be related not only to oral health but also to many systemic diseases such as ...
K. Musilová   +2 more
doaj  

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

open access: yesAdvanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang   +10 more
wiley   +1 more source

Age-stratified differences in coronary artery plaque phenotypes in women and men with non-obstructive coronary artery disease. [PDF]

open access: yesOpen Heart
Hondros CAB   +7 more
europepmc   +1 more source

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

open access: yesAdvanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng   +10 more
wiley   +1 more source

An Erythematous Plaque on the Nose

open access: yesIndian Journal of Dermatology, 2023
Faten Rabhi   +4 more
openaire   +3 more sources

Monitoring the Dynamics of Alzheimer's Disease Biomarkers and the APOE–Tau Axis via Human Cerebral Organoids with Immuno‐SERS

open access: yesAdvanced Science, EarlyView.
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo   +11 more
wiley   +1 more source

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