Results 241 to 250 of about 1,146,198 (394)

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

Advanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He, Hui Min Tay, Feng Chen, Hong Sheng Cheng, Liang De Wang, Qiqi Nam, Arunachalam Thannirmalai, Lingyan Gong, Aram J. Chung, Nguan Soon Tan, King Ho Holden Li, Rinkoo Dalan, Siu Ling Wong, Han Wei Hou   +13 more
wiley   +1 more source

Nanotechnology for atherosclerotic plaque stabilisation: bridging innovation and clinical practice. [PDF]

EBioMedicine
Ren Y, Zhou Y, Xiang B, Li Q, Zhou X.
europepmc   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

Advanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu, Penglei Wang, Gaoyuan Xu, Jitao Lu, Qinke Peng, Danyang Wu, Hequan Sun   +6 more
wiley   +1 more source

Short-Term Outcomes of Visual-Aid-Based Motivation on Children's Oral Hygiene: A Randomized Controlled Trial. [PDF]

Children (Basel)
Candan M, İdacı M, Çamgöz A, Hatipoğlu H, Yılmaz Karaman İG.   +4 more
europepmc   +1 more source

A Phase 3b Study Evaluating Safety and Efficacy of Risankizumab in Adult Patients with Moderate-to-Severe Plaque Psoriasis with Palmoplantar (Non-Pustular) Involvement

, 2023
Mark Lebwohl, Michael Bukhalo, Linda Stein Gold, Michelle T. Pelle, Bradley Glick, Mar Llamas‐Velasco, Samuel Sanchez‐Rivera, Tianyu Zhan, Leonidas Drogaris, Kevin Douglas, Greg St. John, Ramon Espaillat, Robert Bissonnette   +12 more
openalex   +2 more sources

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

Identification of histological carotid plaque vulnerability by CT angiography using perivascular adipose tissue radiomics signature. [PDF]

Insights Imaging
Shu K, Chen J, Li K, Fan X, Zhou L, Wang C, Xu L, Liu Y, Feng Y, Kong D, Fan X, Jiang B, Shao J, Lai Z, Liu B.   +14 more
europepmc   +1 more source

Non-calcified Coronary Plaque in an Asymptomatic Physician [PDF]

, 2009
Samuel Wann
openalex   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Wall Shear Stress Distribution in Intracranial Atherosclerotic Disease and Associations With Vessel and Plaque Morphology. [PDF]

CNS Neurosci Ther
Lan L, Li S, Liu H, H L Ip V, Abrigo J, Tian X, Liu Y, Liu Y, Li Z, Liang T, Fan FSY, Ma SH, Ma K, Y M Ip B, Soo YOY, Leung H, Mok VCT, Fang H, Song B, Xu Y, Fan Y, Leung TW, Leng X.   +22 more
europepmc   +1 more source