Results 271 to 280 of about 1,082,648 (349)

Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline

open access: yesAnnals of Neurology, EarlyView.
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander   +17 more
wiley   +1 more source

Ms4a4a deficiency ameliorates plaque pathology in a mouse model of amyloid accumulation. [PDF]

open access: yesAlzheimers Dement
Danhash EP   +16 more
europepmc   +1 more source

Harnessing Physiological Shear Stress in a Perfusion Bioreactor for Enhanced Endothelialization of Small‐Diameter Vascular Grafts

open access: yesAdvanced NanoBiomed Research, EarlyView.
Traditional static culture provides limited physiological relevance for evaluation of vascular grafts. A perfusion bioreactor system can provide more accurate in vitro model for evaluation of vascular grafts, exposing endothelial cells on 3D structure to physiological or pathological shear stress.
Praveesuda L. Michael   +10 more
wiley   +1 more source

A Photoresponsive Hybrid of Viruses and Supramolecular Peptide Fibers for Multidimensional Control of Patterning and Infection

open access: yesAngewandte Chemie, EarlyView.
A hybrid of a bacteriophage virus and a helical supramolecular fiber, composed of an amphiphilic peptide containing an azobenzene group (A2Az), as a virus hybridizable self‐assembling peptide is reported. The hybrid undergoes disassembly by photo‐induced depolymerization of the A2Az fiber, which enables site‐selective control of the adhesion and ...
Atsuya Yaguchi   +11 more
wiley   +2 more sources

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

open access: yesAdvanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu   +3 more
wiley   +1 more source

Age-stratified differences in coronary artery plaque phenotypes in women and men with non-obstructive coronary artery disease. [PDF]

open access: yesOpen Heart
Hondros CAB   +7 more
europepmc   +1 more source

Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease

open access: yesAdvanced NanoBiomed Research, EarlyView.
Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang   +5 more
wiley   +1 more source

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