Results 271 to 280 of about 1,105,082 (410)

Mannheim Carotid Intima-Media Thickness and Plaque Consensus (2004–2006–2011)

open access: yesCerebrovascular Diseases, 2012
P. Touboul   +20 more
semanticscholar   +1 more source

Direct Sequencing of 5‐Methylcytosine and 5‐Hydroxymethylcytosine at Single‐Base Resolution Unravels Their Distinct Roles in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study introduces two orthogonal sequencing methods, CMD1‐Deaminase sequencing (CD‐seq) and CMD1‐TET bisulfite sequencing (CT‐seq), that enable direct, independent detection of 5mC. Using these approaches together with ACE‐seq or TAB‐seq for 5hmC identification, the study reveals a significant reduction in 5hmC, but not 5mC, in the hippocampus of ...
Zi‐Xin Wang   +15 more
wiley   +1 more source

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

open access: yesAggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky   +3 more
wiley   +1 more source

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu   +4 more
wiley   +1 more source

Optimized DeepLabV3+ for Clinical Data Analysis through Advanced Particle Swarm Optimization‐Based Channel Selection

open access: yesAdvanced Intelligent Systems, EarlyView.
A novel medical image segmentation framework that integrates an enhanced Particle Swarm Optimization (EE‐PSO) into DeepLabV3+ to optimize feature selection. By dynamically identifying key channels in the atrous spatial pyramid pooling module, the method improves segmentation performance, achieving mIoU gains of 2.7% on Alzheimer's and 2.8% on brain ...
Alireza Norouziazad   +8 more
wiley   +1 more source

Ultra-high-resolution and dual-energy computed tomography of carotid artery plaques differentiate symptomatic and asymptomatic patients by novel volumetric analysis. [PDF]

open access: yesInterdiscip Cardiovasc Thorac Surg
Macharzina RR   +12 more
europepmc   +1 more source

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