Lipomatous Hypertrophy of the Interatrial Septum (LHIS) a Biomarker for Cardiovascular Protection? A Hypothesis Generating Case-Control Study. [PDF]
Lacaita PG+6 more
europepmc +1 more source
Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander+17 more
wiley +1 more source
Ms4a4a deficiency ameliorates plaque pathology in a mouse model of amyloid accumulation. [PDF]
Danhash EP+16 more
europepmc +1 more source
Traditional static culture provides limited physiological relevance for evaluation of vascular grafts. A perfusion bioreactor system can provide more accurate in vitro model for evaluation of vascular grafts, exposing endothelial cells on 3D structure to physiological or pathological shear stress.
Praveesuda L. Michael+10 more
wiley +1 more source
A hybrid of a bacteriophage virus and a helical supramolecular fiber, composed of an amphiphilic peptide containing an azobenzene group (A2Az), as a virus hybridizable self‐assembling peptide is reported. The hybrid undergoes disassembly by photo‐induced depolymerization of the A2Az fiber, which enables site‐selective control of the adhesion and ...
Atsuya Yaguchi+11 more
wiley +2 more sources
Developing a novel diagnostic model for identifying high-risk plaques in new onset unstable angina pectoris using coronary CT angiography. [PDF]
Li H+6 more
europepmc +1 more source
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu+3 more
wiley +1 more source
Age-stratified differences in coronary artery plaque phenotypes in women and men with non-obstructive coronary artery disease. [PDF]
Hondros CAB+7 more
europepmc +1 more source
Mechanism of Plaque Inhibition of Poliovirus Possessing the d Marker
Craig Wallis, J. L. Melnick
openalex +1 more source
Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease
Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang+5 more
wiley +1 more source