Results 311 to 320 of about 1,105,082 (410)

Midlife Steroid‐Binding Globulin Levels and In Vivo Neuroimaging Measures of Tau in Older Men and Women

Annals of Neurology, EarlyView.
Objective In men and women, sex steroid hormones have been associated with increased risk of Alzheimer's disease (AD) dementia. We aimed to investigate the influence of midlife testosterone and sex hormone binding globulin (SHBG) levels on later‐life in vivo markers of β‐amyloid (Aβ) and tau deposition in clinically healthy older men. Methods This time‐
Rachel F. Buckley, Matthew Scott, Emer R. McGrath, Gillian Coughlan, Mabel Seto, Saptaparni Ghosh, Heidi I. L. Jacobs, Claudia L. Satizabal, Emma Thibault, Vasan Ramachandran, Joanne M. Murabito, Reisa A. Sperling, Keith A. Johnson, Ravi Jasuja, Shalender Bhasin, Sudha Seshadri, Alexa S. Beiser   +16 more
wiley   +1 more source

Intravascular Coronary Imaging Update: Advances, Clinical Applications, and Future Directions. [PDF]

Curr Cardiol Rep
Waxman S, Bajwa U, Tran M.
europepmc   +1 more source

New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond

Annals of Neurology, EarlyView.
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr., Bruce A. C. Cree, Stephen L. Hauser   +2 more
wiley   +1 more source

Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau PET Clocks

Annals of Neurology, EarlyView.
Objective The objective of this study was to evaluate the timing of change of Alzheimer's disease (AD) plasma biomarkers (Aβ42/Aβ40, p‐tau217, p‐tau181, GFAP, and NfL) from six different assay platforms, alongside established AD biomarkers, using amyloid and tau positron emission tomography (PET)‐based AD progression timelines.
Marta Milà‐Alomà, Duygu Tosun, Suzanne E. Schindler, Isabella Hausle, Kellen K. Petersen, Yan Li, Jeffrey L. Dage, Lei Du‐Cuny, Ziad S. Saad, Benjamin Saef, Gallen Triana‐Baltzer, David L. Raunig, Janaky Coomaraswamy, Michael Baratta, Emily A. Meyers, Yulia Mordashova, Carrie E. Rubel, Kyle Ferber, Hartmuth Kolb, Nicholas J. Ashton, Henrik Zetterberg, Erin G. Rosenbaugh, Martin Sabandal, Leslie M. Shaw, Anthony W. Bannon, William Z. Potter, for the Alzheimer's Disease Neuroimaging Initiative (ADNI), Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium Plasma Aβ and Phosphorylated Tau as Predictors of Amyloid and Tau Positivity in Alzheimer's Disease Project Team   +27 more
wiley   +1 more source

Milia en plaque

Indian Dermatology Online Journal, 2014
Rachita Dhurat, Ganesh Avhad, Smita Ghate   +2 more
openaire   +4 more sources

Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline

Annals of Neurology, EarlyView.
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander, D. Luke Fischer, Lawren VandeVrede, Emma Nichols, Lei Yu, James R. Pike, Walter Swardfager, Che‐Yuan Wu, Mario Masellis, Liisa A. M. Galea, Katherine Zukotynski, Gillian Einstein, Sandra E. Black, Lisa L. Barnes, Julie A. Schneider, Zoe Arvanitakis, Kaitlin B. Casaletto, Jennifer S. Rabin   +17 more
wiley   +1 more source

A firm plaque on the cheek

Indian Dermatology Online Journal, 2016
Kara Melissa T Torres, Frank Ferritto, Dirk M. Elston, Dennis C Polley   +3 more
openaire   +4 more sources

Long‐Circulating Nanobody Confers Durable Prophylaxis against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Infection

Advanced NanoBiomed Research, EarlyView.
This study explores Fc engineering to extend nanobody half‐lives in vivo. Herein, it is demonstrated that the circulation half‐life of Nanosota‐3A‐Fc, a novel nanobody with potent neutralizing activity against SARS‐CoV‐2 Omicron BA.1 variant, can be greatly prolonged by introducing M252Y/S254T/T256E (YTE) substitutions in the IgG1 Fc domain, which ...
Geetha Jyothi Vaskuri, Gang Ye, Fan Bu, Dong Yang, Colleen B. Jonsson, Hailey Turner‐Hubbard, Sydney Winecke, Alise Mendoza, Fang Li, Chalet Tan   +9 more
wiley   +1 more source

Harnessing Physiological Shear Stress in a Perfusion Bioreactor for Enhanced Endothelialization of Small‐Diameter Vascular Grafts

Advanced NanoBiomed Research, EarlyView.
Traditional static culture provides limited physiological relevance for evaluation of vascular grafts. A perfusion bioreactor system can provide more accurate in vitro model for evaluation of vascular grafts, exposing endothelial cells on 3D structure to physiological or pathological shear stress.
Praveesuda L. Michael, Yuen Ting Lam, Timothy C. Mitchell, Miguel Santos, Alex H. P. Chan, Xinying Liu, Angus J. Grant, Matthew J. Moore, David F. Fletcher, Richard P. Tan, Steven G. Wise   +10 more
wiley   +1 more source

Qualitative Plaque Stabilization But Not Quantitative Plaque Regression

Circulation Journal, 2012
openaire   +4 more sources