Identification and Validation of Candidate Gene Module Along With Immune Cells Infiltration Patterns in Atherosclerosis Progression to Plaque Rupture via Transcriptome Analysis. [PDF]
Xu J, Chen C, Yang Y.
europepmc +1 more source
Classification of Carotid Plaque with Jellyfish Sign Through Convolutional and Recurrent Neural Networks Utilizing Plaque Surface Edges [PDF]
In carotid arteries, plaque can develop as localized elevated lesions. The Jellyfish sign, marked by fluctuating plaque surfaces with blood flow pulsation, is a dynamic characteristic of these plaques that has recently attracted attention. Detecting this sign is vital, as it is often associated with cerebral infarction.
arxiv
Time Relationships Between Plaque Rupture and Infarction [PDF]
H. Richard Hellstrom
openalex +1 more source
Background and Purpose Liver X receptors (LXRs) are promising therapeutic targets for alleviating Alzheimer's disease (AD) symptoms. We assessed the impact of the semi‐synthetic LXR agonist 22‐ketositosterol on disease progression in an AD mouse model.
Nikita Martens+15 more
wiley +1 more source
Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases
Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei+5 more
wiley +1 more source
Unraveling Pleiotropic Effects of Statins on Plaque Rupture [PDF]
Wulf Palinski, Claudio Napoli
openalex +1 more source
Advanced Imaging Supports the Mechanistic Role of Autoimmunity and Plaque Rupture in COVID-19 Heart Involvement. [PDF]
Laino ME+9 more
europepmc +1 more source
Inflammation in atherosclerotic cardiovascular disease: From diagnosis to treatment
Inflammation in atherosclerotic cardiovascular disease. Residual inflammatory risk (RIR), defined by high‐sensitive C‐reactive protein (hsCRP) concentration of ≥2 mg/L, represents a strong predictor of future atherosclerotic cardiovascular disease (ASCVD) events. Although increased hsCRP values ≥2 mg/L might be detected in every three out of five ASCVD
Natalie Arnold, Wolfgang Koenig
wiley +1 more source
APOL1 Genetic Variants Are Associated With Increased Risk of Coronary Atherosclerotic Plaque Rupture in the Black Population. [PDF]
Cornelissen A+26 more
europepmc +1 more source