Results 211 to 220 of about 42,323 (259)

Rupture of the Atherosclerotic Plaque

open access: yes
Cullen, Paul   +20 more
openaire   +1 more source

Plaque Rupture and Plaque Erosion

Thrombosis and Haemostasis, 1999
SummaryThere are multiple substrates for coronary thrombosis overlying an atherosclerotic plaque. The most common, plaque rupture, consists of an interruption of a thin fibrous cap overlying a lipid rich core. Plaque rupture is a result of macrophage infiltration and matrix degradation, is often seen in calcified plaques, and is highly associated with ...
R, Virmani, A P, Burke, A, Farb
openaire   +2 more sources

HISTOPATHOLOGY OF PLAQUE RUPTURE

Cardiology Clinics, 1999
Plaque disruption occurs during the development of atherosclerotic lesions. During certain circumstances it may result in thrombosis and subsequent development of acute coronary syndromes. Several characteristics of the plaque appear to be associated with plaque disruption, including a large lipid rich core, superficial plaque inflammation, and a thin ...
Ravn, Hanne Berg, Falk, Erling
openaire   +3 more sources

Carotid plaque rupture

The Lancet, 2009
A 74-year-old man presented with left-sided monocular visual loss as a result of branch retinal artery occlusion. Carotid ultrasonography showed mild (20%) left carotid artery stenosis but no embolic source was identifi ed. MRI of the carotid artery showed a large atherosclerotic plaque at the origin of the left internal carotid artery, despite only ...
Niall G, Keenan   +4 more
openaire   +2 more sources

Echolucent rupture-prone plaques

Current Opinion in Lipidology, 2003
Routine measurement of echolucency of atherosclerotic plaques, in addition to degree of stenosis, may change clinical practice in the future. Within the context of previous knowledge in this field, we therefore review recent developments in detection and histological characterization of echolucent rupture-prone plaques and risk for ischaemic events ...
Børge G, Nordestgaard   +2 more
openaire   +2 more sources

Mouse models of plaque rupture

Current Opinion in Lipidology, 2013
Atherosclerotic plaque destabilization and rupture is an important pathological condition that may account for approximately 70% of acute myocardial infarction cases. To analyse the mechanisms by which an atherosclerotic plaque destabilizes and ruptures and examine the effects of novel therapeutic approaches, several groups have developed mouse models ...
Tetsuya, Matoba   +2 more
openaire   +2 more sources

PATHOPHYSIOLOGY OF PLAQUE RUPTURE AND THE CONCEPT OF PLAQUE STABILIZATION

Cardiology Clinics, 1996
Atherosclerotic coronary artery disease is the major cause of death, in men and women, in the United States and in much of the Western world. Atherosclerosis is responsible for coronary heart disease, limb ischemia, and most strokes. Although luminal narrowing by an atherosclerotic plaque and exaggerated or anomalous vasoconstriction contribute to some
openaire   +3 more sources

Plaque rupture and erosion

2021
Despite improvement in the treatment, prevention, and risk factor management of atherosclerosis, the most frequent cause of death globally remains coronary artery disease. Therefore, it is essential to understand the underlying mechanisms involved in the manifestation of acute coronary syndromes, sudden cardiac death, or stable ischaemic heart disease.
Hiroyoshi Mori, Sho Torii, Renu Virmani
openaire   +1 more source

Endothelial dysfunction in plaque rupture and plaque erosion

Heart and Vessels
Vascular endothelial function plays an important role in the pathophysiology of acute coronary syndrome (ACS). Plaque erosion (PE) and plaque rupture (PR) are the two major mechanisms of ACS; however, how the vascular endothelial function differs between these etiologies is not well understood.
Yuki Ishii   +10 more
openaire   +2 more sources

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