Results 261 to 270 of about 41,607 (304)
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2007
It is widely believed that rupture of a vulnerable atherosclerotic plaque leads to acute coronary events and stroke. However, the exact mechanisms involved in the plaque rupture remain unknown. Pathological animal models are valuable in the research on human disease mechanism, their therapy, and drug development.
Takeshi, Sasaki +2 more
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It is widely believed that rupture of a vulnerable atherosclerotic plaque leads to acute coronary events and stroke. However, the exact mechanisms involved in the plaque rupture remain unknown. Pathological animal models are valuable in the research on human disease mechanism, their therapy, and drug development.
Takeshi, Sasaki +2 more
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Drug Discovery Today: Disease Models, 2007
The most common underlying cause of the acute coronary syndromes is atherosclerotic plaque rupture, which is therefore of major clinical and pathological importance. Further insight into the aetiology of plaque rupture is essential to the development of new therapeutic strategies.
Christopher L. Jackson +3 more
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The most common underlying cause of the acute coronary syndromes is atherosclerotic plaque rupture, which is therefore of major clinical and pathological importance. Further insight into the aetiology of plaque rupture is essential to the development of new therapeutic strategies.
Christopher L. Jackson +3 more
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Genes potentially involved in plaque rupture
Current Opinion in Lipidology, 2002Rupture of an atherosclerotic plaque is the predominant underlying event in the pathogenesis of acute coronary syndromes and stroke. While ruptured plaques are morphologically well described, the precise molecular mechanisms involved in plaque rupture are still incompletely understood.
Birgit C G, Faber +3 more
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Oxysterols, metalloproteases and atherosclerotic plaque rupture
Free Radical Biology and Medicine, 2017A still growing bulk of evidence underlies the multifaceted biochemical properties of oxysterols, several of them of clear relevance to human pathophysiology. Taken up by cells through both vesicular and non vesicular ways or often generated intracellularly, oxysterols contribute to modulate the inflammatory response of a given tissue but also cell ...
GARGIULO, Simona +5 more
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Plaque Rupture, Thrombosis, and Therapeutic Implications
Pathophysiology of Haemostasis and Thrombosis, 1996The basic mechanisms of atherosclerotic progression leading to the acute coronary syndromes (ACS) have been elucidated during the few years. In this brief presentation, we outline 1) Definition of Atherosclerotic Lesions: eight morphologically different lesions are defined (Type I to VI) in various phases of disease.
V, Fuster +3 more
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2002
Background and Pathophysiology Development of the Atherosclerotic Plaque Joan W. Berman, Marwan Kazimi, and Harry Ma Clinical and Pathological Correlates Renu Virmani, Allen P. Burke, Andrew Farb, and Frank D. Kolodgie The Role of Inflammation in Plaque Rupture Anton E. Becker and Allard C.
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Background and Pathophysiology Development of the Atherosclerotic Plaque Joan W. Berman, Marwan Kazimi, and Harry Ma Clinical and Pathological Correlates Renu Virmani, Allen P. Burke, Andrew Farb, and Frank D. Kolodgie The Role of Inflammation in Plaque Rupture Anton E. Becker and Allard C.
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Numerical Simulation of Arterial Plaque Ruptures
International Journal of Material Forming, 2008We present three-dimensional finite element simulations of damaged arteries, used to investigate the influence of the geometry and tissue properties on the plaque rupture. We adopt a baseline geometry reconstructed from a contiguous set of in vitro magnetic resonance images of a damaged artery.
FERRARA, ANNA, PANDOLFI, ANNA MARINA
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Atherosclerosis and plaque rupture
Catheterization and Cardiovascular Interventions, 2001F G, Welt, D I, Simon
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PATHOPHYSIOLOGY OF PLAQUE RUPTURE AND THE CONCEPT OF PLAQUE STABILIZATION
Cardiology Clinics, 1996Atherosclerotic coronary artery disease is the major cause of death, in men and women, in the United States and in much of the Western world. Atherosclerosis is responsible for coronary heart disease, limb ischemia, and most strokes. Although luminal narrowing by an atherosclerotic plaque and exaggerated or anomalous vasoconstriction contribute to some
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Randall’s plaque and calcium oxalate stone formation: role for immunity and inflammation
Nature Reviews Nephrology, 2021Saeed R Khan +2 more
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