Results 341 to 350 of about 755,810 (388)
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Fatigue and plaque rupture in myocardial infarction
Journal of Biomechanics, 2006Plaque rupture plays a role in the majority of acute coronary syndromes. Rupture has been associated with stress concentrations, which are affected by tissue properties and anatomy. In this study rupture was not approached as an acute syndrome, but rather as the culmination of a chronic injury or fatigue process. The aim of our study was to investigate
Alan J. Bank +2 more
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Genes potentially involved in plaque rupture
Current Opinion in Lipidology, 2002Rupture of an atherosclerotic plaque is the predominant underlying event in the pathogenesis of acute coronary syndromes and stroke. While ruptured plaques are morphologically well described, the precise molecular mechanisms involved in plaque rupture are still incompletely understood.
Sylvia Heeneman +3 more
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Is there life after plaque rupture?
Biochemical Society Transactions, 2007Little is known of the relationship between plaque rupture and adaptive geometric remodelling, especially in the context of unstable atherosclerosis. We have assessed remodelling in the proximal brachiocephalic arteries of fat-fed apoE (apolipoprotein E)-knockout mice.
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Psychological Triggers for Plaque Rupture [PDF]
, 2011 Emotional stress has long been suspected as a trigger for myocardial infarction (MI) and sudden cardiac death. An early description of MI published by Obraztsov and Strazhesko in 1910 noted that ‘Direct events often precipitated the disease; the infarct began in one case on climbing a high staircase, in another during an unpleasant conversation, and in
Geoffrey H. Tofler +4 more
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Parallel cholesterol crystals: a sign of impending plaque rupture?
The Journal of invasive cardiology, 2013BACKGROUND Currently, there are no available methods that can reliably predict when or if an atheroma will rupture. Recent reports suggest cholesterol crystals (CCs), present within the necrotic core, are sharp and can penetrate and disrupt the fibrous ...
R. Frink
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Fatigue crack propagation analysis of plaque rupture.
Journal of Biomechanical Engineering, 2013Rupture of atheromatous plaque is the major cause of stroke or heart attack. Considering that the cardiovascular system is a classic fatigue environment, plaque rupture was treated as a chronic fatigue crack growth process in this study.
Xuan Pei, Baijian Wu, Zhiyong Li
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Biomechanical Determinants of Plaque Rupture
ASME 2010 Summer Bioengineering Conference, Parts A and B, 2010Atherosclerosis is an important cardiovascular disease in which plaque build up occurs in a vessel. The rupture of the cap that covers the plaque of a coronary artery is the underlying cause of the majority of fatal acute myocardial infarctions and sudden coronary deaths [1].
Frank J. H. Gijsen +4 more
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Local and Systemic Mechanisms of Plaque Rupture
Angiology, 2008Mechanisms at the basis of coronary plaque instability are still elusive. On the one hand, accumulating data, from clinical and postmortem studies, suggest the role of systemic factors, in particular inflammation, in plaque rupture. On the other hand, local factors, in particular plaque composition, such as a large lipid-rich core and a thin fibrous ...
Luigi M. Biasucci +2 more
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Numerical Simulation of Arterial Plaque Ruptures
International Journal of Material Forming, 2008We present three-dimensional finite element simulations of damaged arteries, used to investigate the influence of the geometry and tissue properties on the plaque rupture. We adopt a baseline geometry reconstructed from a contiguous set of in vitro magnetic resonance images of a damaged artery.
FERRARA, ANNA, PANDOLFI, ANNA MARINA
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