Results 81 to 90 of about 700,142 (373)

Plaque rupture and intact fibrous cap assessed by optical coherence tomography portend different outcomes in patients with acute coronary syndrome.

open access: yesEuropean Heart Journal, 2015
AIMS Patients presenting with acute coronary syndrome (ACS) may have different plaque morphologies at the culprit lesion. In particular, plaque rupture (PR) has been shown as the more frequent culprit plaque morphology in ACS.
G. Niccoli   +12 more
semanticscholar   +1 more source

Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3‐LPL Axis

open access: yesAdvanced Science, EarlyView.
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang   +13 more
wiley   +1 more source

Can OCT change the therapeutic strategy in ACS due to plaque erosion?

open access: yesIndian Heart Journal, 2021
The pathophysiology of acute coronary syndromes was thought to be coronary thrombosis over a plaque rupture. Autopsy studies revealed that not all cases were due to plaque rupture, even denuded endothelium or calcific nodule can beget a thrombus ...
I. Sathyamurthy, G. Sengottuvelu
doaj  

Involvement of Serum Matrix Metalloproteinase-9 in the Pathogenesis of Acute Myocardial Infarction

open access: yesCentral Asian Journal of Medical Sciences, 2016
Objectives: Prior studies indicate that matrix metalloproteinase-9 (MMP-9) plays a key role in pathogenesis of plaque rupture. The objective of this study was to evaluate the involvement of serum MMP-9 enzyme at pathogenesis of the plaque rupture in ...
Sumiya Tserendavaa   +6 more
doaj   +1 more source

Deep learning segmentation of fibrous cap in intravascular optical coherence tomography images [PDF]

open access: yesarXiv, 2023
Thin-cap fibroatheroma (TCFA) is a prominent risk factor for plaque rupture. Intravascular optical coherence tomography (IVOCT) enables identification of fibrous cap (FC), measurement of FC thicknesses, and assessment of plaque vulnerability. We developed a fully-automated deep learning method for FC segmentation.
arxiv  

Multimodality Intravascular Imaging Assessment of Plaque Erosion versus Plaque Rupture in Patients with Acute Coronary Syndrome

open access: yesKorean Circulation Journal, 2016
Background and Objectives We assessed plaque erosion of culprit lesions in patients with acute coronary syndrome in real world practice. Subjects and Methods Culprit lesion plaque rupture or plaque erosion was diagnosed with optical coherence tomography (
J. Kwon   +14 more
semanticscholar   +1 more source

Homocysteine Promotes the Pathogenesis of Atherosclerosis through the Circ‐PIAS1‐5/miR‐219a‐2‐3p/TEAD1 Axis

open access: yesAdvanced Science, EarlyView.
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma   +13 more
wiley   +1 more source

Fluids and flows in brain cancer and neurological disorders

open access: yesWIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023
The different roles of fluids and flow in brain cancer (left) and Alzheimer's disease (right) into and out of the brain and within the interstitial spaces (insets). Abstract Interstitial fluid (IF) and cerebrospinal fluid (CSF) are an integral part of the brain, serving to cushion and protect the brain parenchymal cells against damage and aid in their ...
Peng Jin, Jennifer M. Munson
wiley   +1 more source

Rupture du long fléchisseur du pouce : complication rare de l´ostéosynthèse par plaque anatomique palmaire du radius distal

open access: yesPAMJ Clinical Medicine, 2020
La rupture du long fléchisseur du pouce secondaire à une ostéosynthèse par plaque palmaire est très rare. Elle est généralement due à la proéminence et/ou la position distale de la plaque. Son diagnostic est facile.
Thierno Souleymane Bah   +5 more
doaj   +1 more source

The Spatial Distribution of Plaque Vulnerabilities in Patients with Acute Myocardial Infarction. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVE:Although the plaque characteristics have been recognized in patients with acute myocardial infarction (AMI), the plaque spatial distribution is not well clarified.
Guian Zheng   +11 more
doaj   +1 more source

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