Results 81 to 90 of about 700,142 (373)
AIMS Patients presenting with acute coronary syndrome (ACS) may have different plaque morphologies at the culprit lesion. In particular, plaque rupture (PR) has been shown as the more frequent culprit plaque morphology in ACS.
G. Niccoli+12 more
semanticscholar +1 more source
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang+13 more
wiley +1 more source
Can OCT change the therapeutic strategy in ACS due to plaque erosion?
The pathophysiology of acute coronary syndromes was thought to be coronary thrombosis over a plaque rupture. Autopsy studies revealed that not all cases were due to plaque rupture, even denuded endothelium or calcific nodule can beget a thrombus ...
I. Sathyamurthy, G. Sengottuvelu
doaj
Involvement of Serum Matrix Metalloproteinase-9 in the Pathogenesis of Acute Myocardial Infarction
Objectives: Prior studies indicate that matrix metalloproteinase-9 (MMP-9) plays a key role in pathogenesis of plaque rupture. The objective of this study was to evaluate the involvement of serum MMP-9 enzyme at pathogenesis of the plaque rupture in ...
Sumiya Tserendavaa+6 more
doaj +1 more source
Deep learning segmentation of fibrous cap in intravascular optical coherence tomography images [PDF]
Thin-cap fibroatheroma (TCFA) is a prominent risk factor for plaque rupture. Intravascular optical coherence tomography (IVOCT) enables identification of fibrous cap (FC), measurement of FC thicknesses, and assessment of plaque vulnerability. We developed a fully-automated deep learning method for FC segmentation.
arxiv
Background and Objectives We assessed plaque erosion of culprit lesions in patients with acute coronary syndrome in real world practice. Subjects and Methods Culprit lesion plaque rupture or plaque erosion was diagnosed with optical coherence tomography (
J. Kwon+14 more
semanticscholar +1 more source
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma+13 more
wiley +1 more source
Fluids and flows in brain cancer and neurological disorders
The different roles of fluids and flow in brain cancer (left) and Alzheimer's disease (right) into and out of the brain and within the interstitial spaces (insets). Abstract Interstitial fluid (IF) and cerebrospinal fluid (CSF) are an integral part of the brain, serving to cushion and protect the brain parenchymal cells against damage and aid in their ...
Peng Jin, Jennifer M. Munson
wiley +1 more source
La rupture du long fléchisseur du pouce secondaire à une ostéosynthèse par plaque palmaire est très rare. Elle est généralement due à la proéminence et/ou la position distale de la plaque. Son diagnostic est facile.
Thierno Souleymane Bah+5 more
doaj +1 more source
The Spatial Distribution of Plaque Vulnerabilities in Patients with Acute Myocardial Infarction. [PDF]
OBJECTIVE:Although the plaque characteristics have been recognized in patients with acute myocardial infarction (AMI), the plaque spatial distribution is not well clarified.
Guian Zheng+11 more
doaj +1 more source