Results 81 to 90 of about 755,810 (388)
Two Views on Plaque Rupture [PDF]
Plaque rupture probably is the most important cause of myocardial infarction. Plaque rupture is thought to be precipitated by proteases that attack a weakened fibrous cap overlying an inflamed atherosclerotic plaque. Obviously, plaque rupture is of major interest for atherosclerosis researchers and a major target for development of therapy in the ...
Göran K. Hansson, Donald D. Heistad
openaire +2 more sources
Simultaneous utilization of calix[4]pyrrole‐ and crown ether‐based molecular recognition allows the construction of a high molecular weight alternating supramolecular polymer. This heat processible polymer can be used as a durable and reusable adhesive on glass and steel with temperature‐enhanced adhesion strength without the need for a solvent ...
Deniz Memis, Abdullah Aydogan
wiley +1 more source
Can OCT change the therapeutic strategy in ACS due to plaque erosion?
The pathophysiology of acute coronary syndromes was thought to be coronary thrombosis over a plaque rupture. Autopsy studies revealed that not all cases were due to plaque rupture, even denuded endothelium or calcific nodule can beget a thrombus ...
I. Sathyamurthy, G. Sengottuvelu
doaj
Involvement of Serum Matrix Metalloproteinase-9 in the Pathogenesis of Acute Myocardial Infarction
Objectives: Prior studies indicate that matrix metalloproteinase-9 (MMP-9) plays a key role in pathogenesis of plaque rupture. The objective of this study was to evaluate the involvement of serum MMP-9 enzyme at pathogenesis of the plaque rupture in ...
Sumiya Tserendavaa+6 more
doaj +1 more source
Human serum albumin nanoparticles loaded with phthalocyanine dyes for potential use in photodynamic therapy of atherosclerotic plaques [PDF]
Diseases caused by obstruction or rupture of vulnerable plaques in the arterial walls such as cardiovascular infarction or stroke are the leading cause of death in the world.
Aljarilla, Ana+14 more
core +1 more source
AIMS Patients presenting with acute coronary syndrome (ACS) may have different plaque morphologies at the culprit lesion. In particular, plaque rupture (PR) has been shown as the more frequent culprit plaque morphology in ACS.
G. Niccoli+12 more
semanticscholar +1 more source
Role Of Metalloproteinases in Plaque Rupture
SUMMARYRupture of the fibrous cap over an atherosclerotic plaque is the main cause of myocardial infarctions and strokes. Plaques vulnerable to rupture have a relatively thin fibrous cap, are highly inflamed and contain less structural collagen. This suggests that increased production of proteases, including metalloproteinases (MMPs), in response to ...
openaire +3 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
A Framework for Local Mechanical Characterization of Atherosclerotic Plaques: Combination of Ultrasound Displacement Imaging and Inverse Finite Element Analysis [PDF]
Biomechanical models have the potential to predict plaque rupture. For reliable models, correct material properties of plaque components are a prerequisite.
Akyildiz, A.C. (Ali)+6 more
core +1 more source
Background and Objectives We assessed plaque erosion of culprit lesions in patients with acute coronary syndrome in real world practice. Subjects and Methods Culprit lesion plaque rupture or plaque erosion was diagnosed with optical coherence tomography (
J. Kwon+14 more
semanticscholar +1 more source