Results 31 to 40 of about 32,282 (260)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Metallic droplet impact simulations on plasma-facing components
Nuclear Materials and EnergyMultiphase Navier–Stokes simulations of liquid metal droplets colliding with solid plasma-facing components are carried out in conditions representative of magnetic confinement fusion devices.
L. Vignitchouk, S. Ratynskaia
doaj +1 more source
On the Structural and Chemical Homogeneity of Spark Plasma Sintered Tungsten
Metals, 2019 Tungsten-based materials are the prime candidate plasma-facing materials for future fusion reactors, such as DEMO. Spark plasma sintering is a prospective fabrication technology with several advantageous features.
Jiří Matějíček +8 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Remobilization of tungsten dust from castellated plasma-facing components
Nuclear Materials and Energy, 2017 Studies of tungsten dust remobilization from castellated plasma-facing components can shed light to whether gaps constitute a dust accumulation site with important implications for monitoring but also removal.
M. De Angeli +7 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Effects of a nitrogen seeded plasma on nanostructured tungsten films having fusion-relevant features
Nuclear Materials and Energy, 2020 Nitrogen (N) seeding is routinely applied in tokamaks with tungsten (W) walls to control the power exhaust toward the divertor. Open questions, concerning the interaction of N with W, are the influence of ion energy and W temperature on retention of ...
Andrea Uccello +14 more
doaj +1 more source
Flux dependence of helium retention in clean W(110): Experimental evidence for He self-trapping
Nuclear Materials and Energy, 2023 Helium (He) retention in tungsten (W) is a concern in fusion reactors since it could be detrimental to plasma facing components performance and influence the fusion fuel balance.
A. Dunand +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source