Results 131 to 140 of about 2,422,567 (286)

Auer Rod-Like Inclusions in Reactive Plasma Cells in a Case of Acute Myeloid Leukemia

Turkish Journal of Hematology, 2016
Sarita Pradhan
doaj   +1 more source

Plasma Cell Infiltrate in Liver Allograft Biopsy: Clinical and Histological Implications

Indian Journal of Transplantation
Introduction: The relevance of plasma cells in the allograft liver is of utmost importance and objective assessment of these infiltrates and correlation with other ancillary findings needs to be evaluated.
Neha Agrawal, Archana Rastogi, Chhagan Bihari, Ashok Choudhury, Viniyendra Pamecha   +4 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway

Frontiers in Immunology
IntroductionEstradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses ...
M. Firoz Mian, M. Firoz Mian, Ramtin Ghasemi, Ramtin Ghasemi, Puja Bagri, Puja Bagri, Joshua J. C. McGrath, Joshua J. C. McGrath, Danya Thayaparan, Danya Thayaparan, Maysa Niazy, Maysa Niazy, Denis P. Snider, Denis P. Snider, Charu Kaushic, Charu Kaushic   +15 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

EFFECT OF DIFFERENT ROUTES OF VACCINATION AGAINST NEW-CASTLE DISEASE ON LYMPHOID ORGANS OF BROILERS

Pakistan Veterinary Journal, 2003
This project was designed to compare two routes (intraocular and drinking water) of vaccination against Newcastle disease in ten11s of protection against velogenic field isolate of Newcastle disease virus (NOV), The immune response and morphological ...
R. Salam, A. Aslam. S. A, Khan, K. Saeed1 and G. Saleem
doaj  

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

Frontiers in Immunology
BackgroundRefractory idiopathic nephrotic syndrome (INS), in native kidneys or post-transplant, represents a major therapeutic challenge due to its high risk of progressing to end-stage renal disease.
Hamza Naciri Bennani, Thomas Sandaye, Quentin Charroyer, Quentin Charroyer, Aurelie Etangsale, Henri Vacher Coponat, Henri Vacher Coponat, Marie Julien, Marie Julien, Vincent Mear, Olivier Dunand, Ludovic Di Ascia, Ludovic Di Ascia, Ludovic Di Ascia   +13 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

To treat or not to treat: a state-of-the-art overview of smoldering multiple myeloma

Frontiers in Hematology
Smoldering multiple myeloma (SMM) is a plasma cell disorder characterized by an elevated monoclonal protein and increased bone marrow plasma cells (BMPC) without end-organ damage.
Ayushi Garg, Srinivas Devarakonda
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source