Results 131 to 140 of about 2,393,121 (307)

Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway

open access: yesFrontiers in Immunology
IntroductionEstradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses ...
M. Firoz Mian   +15 more
doaj   +1 more source

Structure of the novel membrane-coating material in proton-secreting epithelial cells and identification as an H+ATPase. [PDF]

open access: yes, 1987
Specialized proton-secreting cells known collectively as mitochondria-rich cells are found in a variety of transporting epithelia, including the kidney collecting duct (intercalated cells) and toad and turtle urinary bladders.
Brown, D, Gluck, S, Hartwig, J
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

EFFECT OF DIFFERENT ROUTES OF VACCINATION AGAINST NEW-CASTLE DISEASE ON LYMPHOID ORGANS OF BROILERS

open access: yesPakistan Veterinary Journal, 2003
This project was designed to compare two routes (intraocular and drinking water) of vaccination against Newcastle disease in ten11s of protection against velogenic field isolate of Newcastle disease virus (NOV), The immune response and morphological ...
R. Salam, A. Aslam. S. A, Khan, K. Saeed1 and G. Saleem
doaj  

Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience

open access: yesFrontiers in Immunology
BackgroundRefractory idiopathic nephrotic syndrome (INS), in native kidneys or post-transplant, represents a major therapeutic challenge due to its high risk of progressing to end-stage renal disease.
Hamza Naciri Bennani   +13 more
doaj   +1 more source

Transfusion-related acute lung injury in multiple traumatized patients [PDF]

open access: yes, 2012
Background: Many of the multiple traumatized patients who refer to the hospital need transfusion. Transfusion-related acute lung injury (TRALI) is a serious clinical syndrome associated with the transfusion of plasma-containing blood components.
Alijanpour, E.   +3 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

To treat or not to treat: a state-of-the-art overview of smoldering multiple myeloma

open access: yesFrontiers in Hematology
Smoldering multiple myeloma (SMM) is a plasma cell disorder characterized by an elevated monoclonal protein and increased bone marrow plasma cells (BMPC) without end-organ damage.
Ayushi Garg, Srinivas Devarakonda
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

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