PTEN restricts IL-21R signaling in GC B cells and suppresses their differentiation to plasma cells. [PDF]
Maldeney AR +8 more
europepmc +1 more source
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah +8 more
wiley +1 more source
Long-lived IgE plasma cells persist in secondary lymphoid tissues using a navitoclax-sensitive survival program. [PDF]
Ding Z +15 more
europepmc +1 more source
Dominant intragraft plasma cells targeting bilirubin implicate local heme catabolism in human cardiac allograft vasculopathy. [PDF]
See SB +24 more
europepmc +1 more source
Rheumatologic Manifestations of Patients With Type B Insulin Resistance
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya +4 more
wiley +1 more source
Next-generation flow cytometry analysis of clonal bone marrow plasma cells identifies an indolent subset of MGUS. [PDF]
Óskarsson JÞ +17 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
B cell maturation antigen (BCMA) is dispensable for the survival of long-lived plasma cells. [PDF]
Menzel SR +10 more
europepmc +1 more source
Duplex Stainless Steel Laser‐Surface Textured: Stability in Brine Solution
Controlled laser‐surface treatment (LST) of duplex DSS2205 steel is performed to increase its stability in brine solution under cyclic electrochemical assays. The superior protection with respect to flat and smooth panels is attributed to the presence of FeCr2O4 as the main protective oxide layer in the LST surface, after corrosion tests. The stability
Mohammad Rezayat +5 more
wiley +1 more source

