Results 141 to 150 of about 813,041 (316)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Investigation of a miniature differential ion thruster [PDF]

open access: yes, 2011
Complex space missions involving formation flying or drag compensation are driving the need for spacecraft propulsion systems capable of providing low but also highly accurate thrust levels.
Collingwood, C., Collingwood, Cheryl
core  

Heterogeneity of Plasma High Density Lipoproteins* [PDF]

open access: yesJournal of Clinical Investigation, 1965
R I, LEVY, D S, FREDRICKSON
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

High-energy dileptons from an anisotropic quark-gluon plasma [PDF]

open access: yes, 2009
We calculate leading-order dilepton yields from a quark-gluon plasma which has a time-dependent anisotropy in momentum space. Such anisotropies can arise during the earliest stages of quark-gluon plasma evolution due to the rapid longitudinal expansion ...
Martinez, Mauricio
core  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Thermal profiles and improved confinement accessibility in RFX-mod and TCV [PDF]

open access: yes, 2013
Humans do not live by bread alone. Physically we are puny creatures with limited prowess, but with unlimited dreams. In the last few decades humankind reached the Moon (1969) and built airports over the sea (1994), but 925 million people are still under-
Scaggion, Alessandro
core  

Real time control of the plasma current and elongation in tokamaks using ECRH actuators [PDF]

open access: yes
Real time control of the plasma elongation and plasma current using electron cyclotron resonance heating (ECRH) actuators has been demonstrated on TCV. Tokamak plasmas may be elongated by off-axis ECRH.
Paley, J. I., Coda, S.
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

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