Results 81 to 90 of about 397,678 (274)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Atomic Data Assessment with PyNeb

Atoms, 2020
PyNeb is a Python package widely used to model emission lines in gaseous nebulae. We take advantage of its object-oriented architecture, class methods, and historical atomic database to structure a practical environment for atomic data assessment.
Christophe Morisset, Valentina Luridiana, Jorge García-Rojas, Verónica Gómez-Llanos, Manuel Bautista, Claudio Mendoza   +5 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Runaway electrons during subnanosecond breakdowns in high-pressure gases

High Voltage, 2016
The parameters of runaway electrons produced in nanosecond high-voltage discharges in different gases (air, nitrogen, sulphur hexafluoride, krypton, argon, methane, neon, hydrogen, helium) at atmospheric and higher pressure were studied.
Victor F. Tarasenko, Mikhail I. Lomaev, Dmitry V. Beloplotov, Dmitry A. Sorokin   +3 more
doaj   +1 more source

Investigating transport of dust particles in plasmas

, 2010
An algorithm has been developped, which makes it possible to automatically extract trajectories of a large number of particles from fast imaging data, allowing a statistical analysis of particles trajectories under various plasma conditions, a better ...
Allen, Basner, Crocker, Hurst, Kalman, Liu, Liu, Nunomura, Peng, Ratynskaia, Robertson, Sezgin, Takamura, Wang, Watanabe, Zafiu   +15 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Diffuse discharges in SF(6) and mixtures of SF(6) with H(2), formed by nanosecond voltage pulses in non-uniform electric field

High Voltage, 2018
Results of experimental study of nanosecond diffuse discharge in SF(6) and gas mixtures of SF(6) with H(2), D(2) and C(2)H(6) are presented. The aim of this work is to study parameters of discharge between two extended electrodes with a small radius of ...
Alexei N. Panchenko, Victor F. Tarasenko, Dmitry V. Beloplotov, Nikolay A. Panchenko, Mikhail I. Lomaev   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

ColRadPy: A Python collisional radiative solver

Nuclear Materials and Energy, 2019
The properties of emitting ions in a plasma provides both potential for plasma diagnostics and key information required for plasma modeling. Generalized collisional radiative theory provides a powerful tool for the modeling of low and moderately dense ...
C.A. Johnson, S.D. Loch, D.A. Ennis
doaj   +1 more source