Results 51 to 60 of about 1,643,465 (296)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Discrimination and visualization of ELM types based on a probabilistic description of inter-ELM waiting times [PDF]
, 2014 Discrimination and visualization of different observed classes of edge-localized plasma instabilities (ELMs), using advanced data analysis techniques has been considered.
Dendy, Richard O +5 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Quantum exchange interaction of spherically symmetric plasmoids
, 2012 We study nano-sized spherically symmetric plasma structures which are radial nonlinear oscillations of electrons in plasma. The effective interaction of these plasmoids via quantum exchange forces between ions is described.
Anderson +27 more
core +1 more source
Stochastic Acceleration of Low Energy Electrons in Plasmas with Finite Temperature [PDF]
, 1997 This paper extends our earlier work on the acceleration of low-energy electrons by plasma turbulence to include the effects of finite temperature of the plasma. We consider the resonant interaction of thermal electrons with the whole transverse branch of
Achatz U. +4 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Scientific Papers Animal Science and Biotechnologies, 2023 The study was conducted to assess the effect of feeding an n-3 PUFA-enriched diet on growth performance, plasma metabolites, and muscle fatty acids composition in growing pigs. Forty growing pigs (13.1±1.8 kg body weight) were randomly divided to receive
Anca Gheorghe +3 more
doaj
Correlation length scalings in fusion edge plasma turbulence computations
, 2011 The effect of changes in plasma parameters, that are characteristic near or at an L-H transition in fusion edge plasmas, on fluctuation correlation lengths are analysed by means of drift-Alfven turbulence computations. Scalings by density gradient length,
A Kendl +12 more
core +1 more source
X-ray emission from MP Muscae: an old classical T Tauri star [PDF]
, 2007 We study the properties of X-ray emitting plasma of MP Mus, an old classical T Tauri star. We aim at checking whether an accretion process produces the observed X-ray emission and at deriving the accretion parameters and the characteristics of the shock ...
A. Maggio +29 more
core +2 more sources
Fast determination of plasma parameters through function parametrization [PDF]
Nuclear Fusion, 1986 The method of function parametrization, developed by H. Wind for fast data evaluation in high energy physics, is demonstrated in the context of controlled fusion research. This method relies on a statistical analysis of a large database of simulated experiments in order to obtain a functional representation for intrinsic physical parameters of a system
Braams, B. J., Jilge, W., Lackner, K.
openaire +6 more sources